Alzheimer's disease (AD) is considered to have a large genetic component. Our knowledge
of this component has progressed over the last 10 years, thanks notably to the advent of …

Highlights•More than 40 loci of interest have been associated with the risk of developing
AD.•Recent genetic data clearly implicate microglia as involved in the pathophysiological …

Abstract Purpose of Review We aimed to summarize the recent advances in genetic findings
of Alzheimer's disease (AD), focusing on traditional single-marker and gene approaches …

The search for the genetic factors contributing to Alzheimer disease (AD) has evolved
tremendously throughout the years. It started from the discovery of fully penetrant mutations …

Alzheimer disease (AD), a progressive and neurodegenerative disease, is the most common
form of dementia with high incidence in elderly people. Neuropathologically the disease is …

Alzheimer's disease (AD) is a clinically heterogeneous neurodegenerative disease with a
strong genetic component. Several genes have been associated with AD risk for nearly 20 …

Alzheimer's disease (AD) is a complex disorder of the central nervous system (CNS).
Molecular genetic research has provided a wealth of information regarding the genetic …

The risk of Alzheimer disease (AD) increases with age, family history and informative genetic
variants. Sadly, there is still no cure or means of prevention. As in other complex diseases …

For two decades the search for genes involved in A lzheimer's disease brought little reward;
it was not until the advent of genome‐wide association studies (GWAS) that genetic …

Linkage studies, candidate gene and whole-genome association studies have resulted in a
tremendous amount of putative risk genes for Alzheimer's disease (AD). Yet, besides the …