Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC) of prostate
and urinary bladder are highly invasive and metastatic tumors of closely neighbored organs …

A limited number of species, including men and dogs, spontaneously develop prostate
cancer (PC). The histological and molecular relevance of canine PC as a model for the …

Controversies remain regarding the cell type from which human prostate cancer originates,
and many attempts have been made to identify the cellular origin of canine prostate cancer …

Background Prostate cancer is a frequent finding in man. In dogs, malignant disease of the
prostate is also of clinical relevance, although it is a less common diagnosis. Even though …

Background In this study we try to identify the origin of canine prostate cancer (cPC) by
classifying the tumors histological subtypes and relate these subtypes to their combined …

BACKGROUND Prostate cancer in men has a high mortality and morbidity due to metastatic
disease. The pathobiology of prostate cancer metastasis is not well understood and cell …

Abstract BACKGROUND In 2012, over 240,000 men were diagnosed with prostate cancer
and over 28,000 died from the disease. Animal models of prostate cancer are vital to …

Background Dog prostate cancer is usually considered to be highly relevant to human
prostate cancer. We report the isolation of a new canine prostate cancer epithelial cell line …

Invasive bladder cancer results in over 10,000 deaths yearly in the United States alone.
More effective therapy for invasive bladder cancer is clearly needed. As new cellular and …

OBJECTIVES: Urinary bladder cancer is the fifth most common form of cancer in humans in
the United States. Urinary bladder cancer also occurs in pet dogs, and naturally-occurring …