Surface Engineering on Bacteria for Tumor Immunotherapy: Strategies and Perspectives

L Fu, Q He, X Lu, L Hu, H Qiang… - Advanced Functional …, 2024 - Wiley Online Library
Bacteria have garnered significant attention in tumor immunotherapy recently years, owing
to their immune‐activating properties, ease of genetic manipulation, and colonization …

Current status and future directions of bacteria-based immunotherapy

Q Tang, X Peng, B Xu, X Zhou, J Chen… - Frontiers in …, 2022 - frontiersin.org
With the in-depth understanding of the anti-cancer immunity, immunotherapy has become a
promising cancer treatment after surgery, radiotherapy, and chemotherapy. As natural …

Surface modification of bacteria to optimize immunomodulation for advanced immunotherapy

K Xue, L Wang, J Liu - ChemMedChem, 2023 - Wiley Online Library
Bacteria have been widely exploited as therapeutic agents for immunotherapy due to their
native immunogenicity, living characteristic, and genetic manipulability. However …

Bacteria-mediated cancer therapies: opportunities and challenges

M Yang, F Yang, W Chen, S Liu, L Qiu, J Chen - Biomaterials Science, 2021 - pubs.rsc.org
In recent years, cancer therapy strategies utilizing live tumor-targeting bacteria have
presented unique advantages. Engineered bacteria have the particular ability to distinguish …

Engineered bacteria in tumor immunotherapy

H Chen, Y Zhu, C Zhang, L Hu, K Yang - Cancer Letters, 2024 - Elsevier
As the limitations of cancer immunotherapy become increasingly apparent, there is
considerable anticipation regarding the utilization of biological tools to enhance treatment …

Surface-modified bacteria: synthesis, functionalization and biomedical applications

S Lin, F Wu, Y Zhang, H Chen, H Guo… - Chemical Society …, 2023 - pubs.rsc.org
The past decade has witnessed a great leap forward in bacteria-based living agents,
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …

Decorated bacteria and the application in drug delivery

F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …

Bacterial‐Mediated Tumor Therapy: Old Treatment in a New Context

Y Liu, L Niu, N Li, Y Wang, M Liu, X Su, X Bao… - Advanced …, 2023 - Wiley Online Library
Targeted therapy and immunotherapy have brought hopes for precision cancer treatment.
However, complex physiological barriers and tumor immunosuppression result in poor …

Recent advances in bacteria-based cancer treatment

X Wei, M Du, Z Chen, Z Yuan - Cancers, 2022 - mdpi.com
Simple Summary Cancer refers to a disease involving abnormal cells that proliferate
uncontrollably and can invade normal body tissue. It was estimated that at least 9 million …

Engineering bacteria for cancer therapy

T Harimoto, T Danino - Emerging topics in life sciences, 2019 - portlandpress.com
The engineering of living cells and microbes is ushering in a new era of cancer therapy. Due
to recent microbiome studies indicating the prevalence of bacteria within the human body …