Diabetes mellitus (DM) is a metabolic illness defined by elevated blood glucose levels,
mediating various tissue alterations, including the dysfunction of vital organs. Diabetes …

Neuropathy is a common complication of diabetes mellitus, which reduces the quality of life
and may be lifethreatening. The etiology is complex and multifactorial: hyperglycemia and …

Type 2 diabetes mellitus (T2D) is a metabolic disorder characterized by inappropriate insulin
function. Despite wide progress in genome studies, defects in gene expression for diabetes …

Diabetes is a metabolic disorder affecting large percentage of population worldwide. NF-κβ
plays key role in pathogenesis of vascular complications of diabetes. Persistent …

Background: The prevalence of diabetes in the world population hás reached 8.8% and is
expected to rise to 10.4% by 2040. Hence, there is an urgent need for the discovery of drugs …

Diabetic kidney disease (DKD) is one of the most common complications of diabetes, and its
prevalence is still growing rapidly. However, the efficient therapies for this kidney disease …

The prevalence of diabetes has reached 8.8% in worldwide population and is predicted to
increase up to 10.4% by 2040. Thus, there is an urgent need for the development of means …

At present, diabetes mellitus (DM) has been one of the most endangering healthy diseases.
Current therapies contain controlling high blood sugar, reducing risk factors like obesity …

Aims/hypothesis The canonical nuclear factor-κB (NF-κB) pathway mediated by the inhibitor
of NF-κB kinase (IKK) regulates the transcription of inflammatory genes involved in the …

Objectives Hyperglycaemia-induced inflammation plays a vital role in the development of
diabetic peripheral neuropathy (DPN). Recent evidences had reported the involvement of …