Cardiovascular pathologies are still the primary cause of death worldwide. The molecular
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …

Abstract Type 2 diabetes (T2D) is one of the most widely spread metabolic disordersand is
also referred as a 'lifestyle'disorder. According toa study conducted by IDB, the number of …

Diabetes mellitus is considered a metabolic disorder characterized by high blood sugar.
Active disease is associated with low grade chronic inflammation resulting from the …

NF-κB pathway consists of canonical and non-canonical pathways. The canonical NF-κB is
activated by various stimuli, transducing a quick but transient transcriptional activity, to …

A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …

Diabetes is a chronic disease that induces many comorbidities, including cardiovascular
disease, nephropathy, and liver damage. Many mechanisms have been suggested as to …

The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …

Aims Nuclear factor-κB (NF-κB) is a transcription factor induced by a wide range of stimuli,
including hyperglycaemia and pro-inflammatory cytokines. It is associated with cardiac …

Diabetes is a metabolic, endocrine disorder which is characterized by hyperglycemia and
glucose intolerance due to insulin resistance. Extensive research has confirmed that …

The nuclear factor kappa B (NF-κB) pathway has emerged as a pivotal player in the
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …