DNA methylation patterns were evaluated during preimplantation mouse development by
analyzing the binding of monoclonal antibody to 5-methylcytosine (5-MeC) on metaphase …

Virtually all mammalian species including mouse, rat, pig, cow, and human, but not sheep
and rabbit, undergo genome‐wide epigenetic reprogramming by demethylation of the male …

Methylation patterns of specific genes have been studied by polymerase chain reaction and
found to undergo dynamic changes in the germ line and early embryo. Some CpG sites are …

During early mouse development, there are large-scale changes in DNA methylation. These
changes may be due to the availability or stability of the enzyme, DNA methyltransferase …

Gene-specific methylation patterns in mammals play a role in a variety of biological
processes in the embryo and adult tissues. These patterns are established during embryo …

A large number of studies have documented the methylation patterns of individual genes
and repeated sequences in different tissues of various mammalian species. This has …

Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …

In mammals, active demethylation of cytosine methylation in the sperm genome prior to
forming a functional zygotic nucleus is thought to be a function of the oocyte cytoplasm …

There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …

This paper shows stage-and tissue-specific global demethylation and remethylation
occurring during embryonic development. The egg genome is strikingly undermethylated …