Increased prevalence of potential right‐to‐left shunting in children with sickle cell anaemia and stroke

MM Dowling, CT Quinn, C Ramaciotti… - British journal of …, 2017 - Wiley Online Library
Summary 'Paradoxical'embolization via intracardiac or intrapulmonary right‐to‐left shunts
(RLS) is an established cause of stroke. Hypercoagulable states and increased right heart …

Prevalence of intracardiac shunting in children with sickle cell disease and stroke

MM Dowling, N Lee, CT Quinn, ZR Rogers… - The Journal of …, 2010 - Elsevier
OBJECTIVE: To determine the prevalence of potential intracardiac shunts, including patent
foramen ovale (PFO), in children with sickle cell disease (SCD) and stroke. STUDY DESIGN …

Defining stroke risk in children with sickle cell anaemia

C Hoppe - British journal of haematology, 2005 - Wiley Online Library
Sickle cell anaemia (SCA) is the most common cause of childhood stroke, occurring with the
highest frequency before the age of 6 years. Despite the relative frequency of stroke in SCA …

Outcome of overt stroke in sickle cell anaemia, a single institution's experience

S Majumdar, M Miller, M Khan… - British journal of …, 2014 - Wiley Online Library
Stroke is a traumatic complication in sickle cell anaemia (SCA) that is associated with
significant morbidity and a risk of recurrent overt stroke of 2· 2–6· 4 events per 100 patient …

Silent cerebral infarcts in very young children with sickle cell anaemia are associated with a higher risk of stroke

MI Cancio, KJ Helton, JE Schreiber… - British journal of …, 2015 - Wiley Online Library
Silent cerebral infarctions (SCI) are the most common neurological injury in children with
sickle cell anaemia (SCA), but their incidence/prognosis in early childhood has not been …

Distinct HLA associations by stroke subtype in children with sickle cell anemia

C Hoppe, W Klitz, J Noble, L Vigil… - Blood, The Journal …, 2003 - ashpublications.org
Children with sickle cell anemia (SCA) carry a 200-fold increased risk for cerebral infarction.
Stroke can be the result of small-vessel (SV) or large-vessel (LV) disease. However, it is …

Children with sickle cell anemia with normal transcranial Doppler ultrasounds and without silent infarcts have a low incidence of new strokes

LC Jordan, DO Roberts Williams… - American journal of …, 2018 - Wiley Online Library
In a prospective cohort study, we tested the hypothesis that children with sickle cell anemia
(SCA) with normal transcranial Doppler ultrasound (TCD) velocities and without silent …

Stroke in sickle cell anemia: alternative etiologies

MM Dowling, CT Quinn, ZR Rogers, JM Journeycake - Pediatric neurology, 2009 - Elsevier
Stroke is common in children with sickle cell anemia, but is rarely attributed to the traditional
causes of stroke identified in other children. An 11-year-old girl with sickle cell anemia …

Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressure

MR DeBaun, SA Sarnaik, MJ Rodeghier… - Blood, The Journal …, 2012 - ashpublications.org
The most common form of neurologic injury in sickle cell anemia (SCA) is silent cerebral
infarction (SCI). In the Silent Cerebral Infarct Multi-Center Clinical Trial, we sought to identify …

[HTML][HTML] Thrombospondin-1 and L-selectin are associated with silent cerebral infarct in children with sickle cell anaemia

LM Faulcon, Z Fu, P Dulloor… - British journal of …, 2013 - ncbi.nlm.nih.gov
Thrombospondin-1 and L-selectin are Associated with Silent Cerebral Infarct in Children with
Sickle Cell Anaemia - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …