RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

Small-molecule and protein/antibody drugs mainly act on genome-derived proteins to exert
pharmacological effects. RNA based therapies hold the promise to expand the range of …

In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …

After over a decade of development, mRNA has recently matured into a potent modality for
therapeutics. The advantages of mRNA therapeutics, including their rapid development and …

RNA-based therapies, including RNA molecules as drugs and RNA-targeted small
molecules, offer unique opportunities to expand the range of therapeutic targets. Various …

In the past decade, RNA therapeutics have gone from being a promising concept to one of
the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what …

ABSTRACT RNA-based therapeutics are emerging as a powerful platform for the treatment
of multiple diseases. Currently, the two main categories of nucleic acid therapeutics …

Oligonucleotide-based therapeutics have attracted attention as an emerging modality that
includes the modulation of genes and their binding proteins related to diseases, allowing us …

The surprising discovery that RNAs are the predominant gene products to emerge from the
human genome catalyzed a renaissance in RNA biology. It is now well-understood that …

Ribonucleic acid (RNA) therapeutics are being actively researched as a therapeutic
modality in preclinical and clinical studies. They have become one of the most ubiquitously …