X-linked mental retardation (XLMR) affects one in 600 males and is highly heterogeneous.
We describe here a 29-year-old woman with severe nonsyndromic mental retardation and a …

In several families with non-specific X-linked mental retardation (XLMR) linkage analyses
have assigned the underlying gene defect to the pericentromeric region of the X …

X-linked mental retardation (XLMR) is a heterogeneous disorder that affects approximately 2
in 1000 males. JARID1C/SMCX is relatively new among the known XLMR genes, and seven …

In families with nonsyndromic X-linked mental retardation (NS-XLMR),> 30% of mutations
seem to cluster on proximal Xp and in the pericentric region. In a systematic screen of brain …

A female patient with non-syndromic mental retardation was shown by high resolution GTL
banding to have inherited an apparently balanced translocation, 46, X, t (X; 8)(q28; q12) …

Background: Mutations in the JARID1C (Jumonji AT-rich interactive domain 1C) gene were
recently associated with X-linked mental retardation (XLMR). Mutations in this gene are …

METHODS A large family is described in which mental retardation segregates as an X linked
trait. Six affected males in three generations were studied by linkage and clinical …

Detailed molecular characterization of chromosomal rearrangements involving X‐
chromosome has been a key strategy in identifying X‐linked intellectual disability‐causing …

X-linked mental retardation (XLMR) is an inherited disorder that mostly affects males and is
caused by mutations in genes located on the X chromosome. Here, we show that the XLMR …

A previously unrecognised X-chromosomal mental retardation syndrome is described.
Clinical hallmarks are mental retardation, epileptic seizures, hypogonadism, and-genitalism …