Excessive surgical stress and postoperative complications cause a storm of perioperative
cytokine release, which has been shown to enhance tumor metastasis in experimental …

We investigated the relationship between surgical stress and tumor metastasis. The
excessive surgical stress of a thoracolaparotomy enhanced tumor metastasis remarkably in …

Despite advances in systemic therapies, surgery is crucial for the management of solid
malignancy. There is increasing evidence suggesting that the body's response to surgical …

Surgical resection is an important avenue for cancer treatment, which, in most cases, can
effectively alleviate the patient symptoms. However, accumulating evidence has …

Despite undergoing a curative resection, many patients with colorectal cancer will develop
and die of metastatic disease. It has been shown clinically and experimentally that surgery …

Surgery is a crucial intervention and provides a chance of cure for patients with cancer. The
perioperative period is characterized by an increased risk for accelerated growth of …

Background: Surgical procedures, including primary tumor resection, have been suggested
to suppress immune competence and to promote postoperative infections and cancer …

Surgery for the removal of a primary tumor presents an opportunity to eradicate cancer or
arrest its progression, but is also believed to promote the outbreak of pre-existing …

Cancer, currently the leading cause of death in the population aged less than 85 years,
poses a significant global disease burden and is anticipated to continue to increase in …

Surgery remains a main part of the treatment of most solid tumors. Paradoxically, rapid
disease progression may be a consequence of surgery in patients presenting with a …