Higher soluble CD163 in blood is associated with significant depression symptoms in men with HIV

AM Anderson, F Bhondoekhan… - JAIDS Journal of …, 2022 - journals.lww.com
Background: People with HIV (PWH) are more likely to experience depression, a highly
morbid disease. More evidence is needed to better understand mechanisms of depression …

Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection

TH Burdo, A Weiffenbach, SP Woods, S Letendre… - Aids, 2013 - journals.lww.com
Objective: Here we evaluated whether neurocognitive disorders in HIV-infected individuals
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …

Soluble CD163 predicts incident chronic lung, kidney and liver disease in HIV infection

DM Kirkegaard-Klitbo, N Mejer, TB Knudsen, HJ Møller… - Aids, 2017 - journals.lww.com
Objective: To examine if monocyte and macrophage activity may be on the mechanistic
pathway to non-AIDS comorbidity by investigating the associations between plasma-soluble …

Plasma soluble CD163 level independently predicts all-cause mortality in HIV-1–infected individuals

TB Knudsen, G Ertner, J Petersen… - The Journal of …, 2016 - academic.oup.com
Abstract Background. CD163, a monocyte-and macrophage-specific scavenger receptor, is
shed as soluble CD163 (sCD163) during the proinflammatory response. Here, we assessed …

[HTML][HTML] Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals

E Tippett, WJ Cheng, C Westhorpe, PU Cameron… - PloS one, 2011 - journals.plos.org
CD163, a haptoglobin-hemoglobin (Hp-Hb) scavenger receptor, expressed by monocytes
and macrophages, is important in resolution of inflammation. Age-related non-AIDS co …

[HTML][HTML] Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms

AM Rakshasa-Loots, N Bakewell, DJ Sharp… - Translational …, 2023 - ncbi.nlm.nih.gov
People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …

[HTML][HTML] Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms

A Mudra Rakshasa-Loots, N Bakewell, DJ Sharp… - Translational …, 2023 - nature.com
People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …

Inflammation and risk of depression in HIV: prospective findings from the Multicenter AIDS Cohort Study

H Lu, PJ Surkan, MR Irwin, GJ Treisman… - American journal of …, 2019 - academic.oup.com
Studies suggest that inflammation might be involved in the pathogenesis of depression.
Individuals with human immunodeficiency virus (HIV) have a higher risk of depression and …

C-reactive protein and depression in persons with human immunodeficiency virus infection: the Positive Living with HIV (POLH) Study

K Poudel-Tandukar, ER Bertone-Johnson… - Brain, behavior, and …, 2014 - Elsevier
Abstract Background Human Immunodeficiency Virus (HIV) infection has been frequently
associated with chronic inflammation as well as depression. C-reactive protein (CRP) is …

Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy

TH Burdo, MR Lentz, P Autissier… - Journal of Infectious …, 2011 - academic.oup.com
CD163, a monocyte-and macrophage-specific scavenger receptor, is shed during activation
as soluble CD163 (sCD163). We have previously demonstrated that monocyte expansion …