[HTML][HTML] Signaling pathways in rheumatoid arthritis: implications for targeted therapy
Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …
progression leads to joint deformity and associated loss of function, which significantly …
Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis
S Liu, H Ma, H Zhang, C Deng, P Xin - Clinical Immunology, 2021 - Elsevier
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …
[HTML][HTML] Promising therapeutic targets for treatment of rheumatoid arthritis
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …
Treatment of rheumatoid arthritis: unraveling the conundrum
E Zampeli, PG Vlachoyiannopoulos, AG Tzioufas - Journal of autoimmunity, 2015 - Elsevier
Rheumatoid arthritis (RA) is a heterogeneous disease with a complex and yet not fully
understood pathophysiology, where numerous different cell-types contribute to a destructive …
understood pathophysiology, where numerous different cell-types contribute to a destructive …
Current understanding of rheumatoid arthritis therapy
I Colmegna, BR Ohata… - Clinical Pharmacology & …, 2012 - Wiley Online Library
Progress in understanding the cellular and molecular mechanisms of rheumatoid arthritis
(RA), together with the availability of new therapies, has changed the way we think about …
(RA), together with the availability of new therapies, has changed the way we think about …
[HTML][HTML] The therapeutic landscape of rheumatoid arthritis: current state and future directions
S Shams, JM Martinez, JRD Dawson, J Flores… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …
emotional and socioeconomic consequences. Despite advances in targeted biologic and …
[HTML][HTML] Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies
AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …
progressive autoimmune disease affecting many people worldwide. While patients show …
[PDF][PDF] Pathogenesis of rheumatoid arthritis: One year in review 2023
FM Mariani, I Martelli, F Pistone… - Clin. Exp …, 2023 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by local and
systemic inflammation. The complex interplay between immune cells and soluble mediators …
systemic inflammation. The complex interplay between immune cells and soluble mediators …
Signal transduction networks in rheumatoid arthritis
D Hammaker, S Sweeney, GS Firestein - Annals of the rheumatic …, 2003 - ard.bmj.com
Signal transduction pathways regulate cellular responses to stress and play a critical role in
inflammation. The complexity and specificity of signalling mechanisms represent major …
inflammation. The complexity and specificity of signalling mechanisms represent major …
Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by a failure of
spontaneous resolution of inflammation. Although the pro-inflammatory cytokines and …
spontaneous resolution of inflammation. Although the pro-inflammatory cytokines and …