Somatostatin sst2 receptor knock-out mice: localisation of sst1–5 receptor mRNA and binding in mouse brain by semi-quantitative RT–PCR, in situ hybridisation …
JP Hannon, C Petrucci, D Fehlmann, C Viollet… - …, 2002 - Elsevier
The peptide hormone/neurotransmitter somatostatin (somatotropin release inhibiting factor;
SRIF) and its receptors (sst1–sst5) appear to regulate many physiological functions in the …
SRIF) and its receptors (sst1–sst5) appear to regulate many physiological functions in the …
Cloning, expression and pharmacological characterisation of the mouse somatostatin sst5 receptor
D Feuerbach, D Fehlmann, C Nunn, S Siehler… - …, 2000 - Elsevier
The mouse somatostatin (somatotropin release inhibiting factor, SRIF) sst5 receptor coding
sequence was cloned from a mouse BALB/c genomic library. It shows 97% and 81 …
sequence was cloned from a mouse BALB/c genomic library. It shows 97% and 81 …
Immunohistochemical localization of the somatostatin sst4 receptor in rat brain
IS Selmer, M Schindler, PPA Humphrey, PC Emson - Neuroscience, 2000 - Elsevier
The biological actions of the neuromodulator somatostatin are mediated through a family of
G-protein-coupled receptors, of which five members, sst1–5, have been identified. Although …
G-protein-coupled receptors, of which five members, sst1–5, have been identified. Although …
Distribution and characterisation of somatostatin receptor mRNA and binding sites in the brain and periphery
D Fehlmann, D Langenegger, E Schuepbach… - Journal of Physiology …, 2000 - Elsevier
The distribution and nature of (somatostatin) SRIF receptors and receptor mRNAs was
studied in the brain and periphery of various laboratory animals using in situ hybridisation …
studied in the brain and periphery of various laboratory animals using in situ hybridisation …
Characterization and distribution of somatostatin SS-1 and SRIF-1 binding sites in rat brain: identitity with SSTR-2 receptors
P Schoeffter, J Pérez, D Langenegger… - European Journal of …, 1995 - Elsevier
Somatostatin (SRIF) SS-1 binding sites were initially defined in radioligand binding studies
performed in rat brain cerebral cortex membranes using [125I] 204-090 (a radiolabelled Tyr3 …
performed in rat brain cerebral cortex membranes using [125I] 204-090 (a radiolabelled Tyr3 …
Somatostatin-induced regulation of SST2A receptor expression and cell surface availability in central neurons: role of receptor internalization
To investigate the effects of somatostatin (somatotropin release-inhibiting factor, SRIF) on
the regulation of SST2A receptors in mammalian brain, we examined how blockade of SRIF …
the regulation of SST2A receptors in mammalian brain, we examined how blockade of SRIF …
Pharmacological identity between somatostatin SS-2 binding sites and SSTR-1 receptors
D Hoyer, J Perez, P Schoeffter, D Langenegger… - European Journal of …, 1995 - Elsevier
Somatostatin (SRIF) SS-2 binding sites were originally defined in rat brain cerebral cortex
membranes using [125I] Tyr11-SRIF-14 in the presence of 120 mM NaCl. These sites were …
membranes using [125I] Tyr11-SRIF-14 in the presence of 120 mM NaCl. These sites were …
Embryonic and postnatal mRNA distribution of five somatostatin receptor subtypes in the rat brain
VS Thoss, J Ferez, D Duc, D Hoyer - Neuropharmacology, 1995 - Elsevier
The messenger RNA (mRNA) expression of somatostatin (SRIF) receptors SSTR-1, SSTR-2,
SSTR-3, SSTR-4 and SSTR-5 (called sst1–5, now) was studied in rat brain between …
SSTR-3, SSTR-4 and SSTR-5 (called sst1–5, now) was studied in rat brain between …
First localisation of somatostatin sst4 receptor protein in selected human brain areas: an immunohistochemical study
IS Selmer, M Schindler, PPA Humphrey… - Molecular brain …, 2000 - Elsevier
Somatostatin is known to have diverse neurophysiological effects in the mammalian CNS.
To date, genes for five different receptors, termed sst1–5, have been isolated. Recently …
To date, genes for five different receptors, termed sst1–5, have been isolated. Recently …
Preferential expression of sst2A over sst2B somatostatin receptor splice variant in rat brain and pituitary
The expression of sst2A and sst2B somatostatin (SRIH) receptor splice variants was
examined by polymerase chain reaction (PCR) in rat brain and pituitary. Two sets of primers …
examined by polymerase chain reaction (PCR) in rat brain and pituitary. Two sets of primers …
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