Endothelial dysfunction: from molecular mechanisms to measurement, clinical implications, and therapeutic opportunities
ML Brocq, SJ Leslie, P Milliken… - Antioxidants & redox …, 2008 - liebertpub.com
Endothelial dysfunction has been implicated as a key factor in the development of a wide
range of cardiovascular diseases, but its definition and mechanisms vary greatly between …
range of cardiovascular diseases, but its definition and mechanisms vary greatly between …
Roles of endothelial dysfunction in coronary artery disease
MA Forgione, JA Leopold… - Current opinion in …, 2000 - journals.lww.com
Endothelial dysfunction is an early and persistent vascular abnormality in the evolution of
atherothrombotic disease. Risk factors for atherosclerosis promote an inflammatory oxidative …
atherothrombotic disease. Risk factors for atherosclerosis promote an inflammatory oxidative …
Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction
T Münzel, C Sinning, F Post, A Warnholtz… - Annals of …, 2008 - Taylor & Francis
Endothelial dysfunction (ED) in the setting of cardiovascular risk factors such as
hypercholesterolemia, hypertension, diabetes mellitus, chronic smoking as well as in …
hypercholesterolemia, hypertension, diabetes mellitus, chronic smoking as well as in …
Endothelial functions
S Godo, H Shimokawa - Arteriosclerosis, thrombosis, and vascular …, 2017 - Am Heart Assoc
The endothelium plays important roles in modulating vascular tone by synthesizing and
releasing a variety of endothelium-derived relaxing factors, including vasodilator …
releasing a variety of endothelium-derived relaxing factors, including vasodilator …
Endothelial dysfunction in atherosclerotic cardiovascular diseases and beyond: from mechanism to pharmacotherapies
The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …
maintaining multiorgan health and homeostasis. Endothelial functions in health include …
Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets
MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …
Endothelial dysfunction in conduit arteries and in microcirculation. Novel therapeutic approaches
D Tousoulis, C Simopoulou, N Papageorgiou… - Pharmacology & …, 2014 - Elsevier
The vascular endothelium not only is a single monolayer of cells between the vessel lumen
and the intimal wall, but also plays an important role by controlling vascular function and …
and the intimal wall, but also plays an important role by controlling vascular function and …
Endothelial function and oxidative stress in cardiovascular diseases
Y Higashi, K Noma, M Yoshizumi, Y Kihara - Circulation journal, 2009 - jstage.jst.go.jp
The vascular endothelium is involved in the release of various vasodilators, including nitric
oxide (NO), prostacyclin and endothelium-derived hyperpolarizing factor, as well as …
oxide (NO), prostacyclin and endothelium-derived hyperpolarizing factor, as well as …
Oxidative stress and endothelial dysfunction in vascular disease
S Pennathur, JW Heinecke - Current diabetes reports, 2007 - Springer
In response to physiologic stimuli, endothelial cells dynamically regulate arterial vascular
tone by producing vasodilators and vasoconstrictors. Risk factors for atherosclerosis, such …
tone by producing vasodilators and vasoconstrictors. Risk factors for atherosclerosis, such …
Endothelial dysfunction and cardiovascular disease: History and analysis of the clinical utility of the relationship
The endothelium is the single-cell monolayer that lines the entire vasculature. The
endothelium has a barrier function to separate blood from organs and tissues but also has …
endothelium has a barrier function to separate blood from organs and tissues but also has …
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