[HTML][HTML] Docosahexaenoic acid regulates the formation of lipid rafts: A unified view from experiment and simulation
SR Wassall, X Leng, SW Canner… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Abstract Docosahexaenoic acid (DHA, 22: 6) is an n− 3 polyunsaturated fatty acid (n− 3
PUFA) that influences immunological, metabolic, and neurological responses through …
PUFA) that influences immunological, metabolic, and neurological responses through …
Docosahexaenoic acid domains: the ultimate non-raft membrane domain
SR Wassall, W Stillwell - Chemistry and physics of lipids, 2008 - Elsevier
What distinguishes polyunsaturated fatty acids (PUFAs) from less unsaturated fatty acids is
the presence of a repeating CH–CH2–CH unit that produces an extremely flexible structure …
the presence of a repeating CH–CH2–CH unit that produces an extremely flexible structure …
[HTML][HTML] Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains
JA Williams, SE Batten, M Harris, BD Rockett… - Biophysical journal, 2012 - cell.com
Omega-3 polyunsaturated fatty acids (n-3 PUFA), enriched in fish oils, are increasingly
recognized to have potential benefits for treating many human afflictions. Despite the …
recognized to have potential benefits for treating many human afflictions. Despite the …
[HTML][HTML] DHA modifies the size and composition of raftlike domains: a solid-state 2H NMR study
JJ Kinnun, R Bittman, SR Shaikh, SR Wassall - Biophysical journal, 2018 - cell.com
Docosahexaenoic acid is an omega-3 polyunsaturated fatty acid that relieves the symptoms
of a wide variety of chronic inflammatory disorders. The structural mechanism is not yet …
of a wide variety of chronic inflammatory disorders. The structural mechanism is not yet …
Differential incorporation of docosahexaenoic acid into distinct cholesterol-rich membrane raft domains
Y Duraisamy, D Lambert, CA O'Neill… - … and biophysical research …, 2007 - Elsevier
We investigated the influence of docosahexaenoic acid (DHA) on the fatty acid and protein
compositions of two populations of membrane rafts present in Caco-2 cells. DHA (100μM) …
compositions of two populations of membrane rafts present in Caco-2 cells. DHA (100μM) …
[HTML][HTML] Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study
SR Shaikh, AC Dumaual, A Castillo, D LoCascio… - Biophysical journal, 2004 - cell.com
We have previously suggested that the ω-3 polyunsaturated fatty acid, docosahexaenoic
acid (DHA) may in part function by enhancing membrane lipid phase separation into lipid …
acid (DHA) may in part function by enhancing membrane lipid phase separation into lipid …
[HTML][HTML] Polyunsaturated lipids regulate membrane domain stability by tuning membrane order
The plasma membrane (PM) serves as the functional interface between a cell and its
environment, hosting extracellular signal transduction and nutrient transport among a variety …
environment, hosting extracellular signal transduction and nutrient transport among a variety …
[HTML][HTML] Docosahexaenoic acid enhances segregation of lipids between raft and nonraft domains: 2H-NMR study
SP Soni, DS LoCascio, Y Liu, JA Williams, R Bittman… - Biophysical journal, 2008 - cell.com
Solid-state 2 H-NMR of [2 H 31]-N-palmitoylsphingomyelin ([2 H 31] 16: 0SM, PSM*),
supplemented by differential scanning calorimetry, was used for the first time, to our …
supplemented by differential scanning calorimetry, was used for the first time, to our …
[HTML][HTML] Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells
SR Shaikh, BD Rockett, K Carraway - The Journal of nutrition, 2009 - Elsevier
An emerging molecular mechanism by which docosahexaenoic acid (DHA) exerts its effects
is modification of lipid raft organization. The biophysical model, based on studies with …
is modification of lipid raft organization. The biophysical model, based on studies with …
Molecular organization of a raft-like domain in a polyunsaturated phospholipid bilayer: A supervised machine learning analysis of molecular dynamics simulations
SW Canner, SE Feller, SR Wassall - The Journal of Physical …, 2021 - ACS Publications
Numerous health benefits are associated with omega-3 polyunsaturated fatty acids (n-3
PUFA) consumed in fish oils. An understanding of the mechanism remains elusive. The …
PUFA) consumed in fish oils. An understanding of the mechanism remains elusive. The …
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