Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …

Cancer is a wide collection of diseases and among the numerous pathways involved in
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …

Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …

Here, we present the design, synthesis, and evaluation of a new series of 1H-benzo [d]
imidazole derivatives (10a–j) to determine their anticancer efficacy. The MCF-7 and HCT116 …

Background: The Epidermal Growth Factor Receptor (known as EGFR) induces cell
differentiation and proliferation upon activation through the binding of its ligands. Since …

This study was focused on the synthesis of new pyrimidines 4a, b, 5a, b and pyrazoles 6a, b
as ATP mimicking tyrosine kinase inhibitors of the epidermal growth factor receptor (EGFR) …

The epidermal growth factor receptor (EGFR) plays a critical role in the tumorigenesis of
various forms of cancer. Targeting the mutant forms of EGFR has been identified as an …

A search for anticancer agents has prompted the design and synthesis of new chalcone,
pyrazoline and pyrimidine derivatives as potential epidermal growth factor receptor (EGFR) …

Almost 80% of lung cancer diagnoses each year correspond to non-small cell lung cancer
(NSCLC). The percentage of NSCLC with EGFR overexpression ranges from 40% to 89 …

The role played by overexpression of tyrosine kinase epidermal growth factor receptor
(EGFR), the transmembrane receptor central to numerous cellular processes comprising cell …