Alzheimer's disease (AD) and bipolar disorder (BD) are progressive brain disorders.
Upregulated mRNA and protein levels of neuroinflammatory and arachidonic acid (AA) …

Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component
but unknown pathophysiology. We used microarray technology to determine the expression …

Previous studies have implicated a number of biochemical pathways in the etiology of
bipolar disorder (BD). However, the precise abnormalities underlying this disorder remain to …

Increasing evidence suggests that epigenetic factors have critical roles in gene regulation in
neuropsychiatric disorders and in aging, both of which are typically associated with a wide …

Reports of cognitive decline, symptom worsening and brain atrophy in bipolar disorder (BD)
suggest that the disease progresses over time. The worsening neuropathology may involve …

Bipolar disorder (BD) is a severe mental disorder characterized by repeated mood swings.
Although genetic factors are collectively associated with the etiology of BD, the underlying …

We performed the oligonucleotide microarray analysis in bipolar disorder, major depression,
schizophrenia, and control subjects using postmortem prefrontal cortices provided by the …

In recent years, numerous studies of gene regulation mechanisms have emerged in
neuroscience. Epigenetic modifications, described as heritable but reversible changes …

Objectives Evidence suggests accelerated aging mechanisms in bipolar disorder (BD),
including DNA methylation (DNAm) aging in blood. However, it is unknown whether such …

Psychiatric disorders are complex multifactorial illnesses involving chronic alterations in
neural circuit structure and function as well as likely abnormalities in glial cells. While …