Piwis and piwi‐interacting RNAs in the epigenetics of cancer

S Siddiqi, I Matushansky - Journal of cellular biochemistry, 2012 - Wiley Online Library
An increasing body of evidence suggests that cancer cells acquire “stem‐like” epigenetic
and signaling characteristics during the tumorigenic process, including global DNA hypo …

[PDF][PDF] PIWI proteins and PIWI-interacting RNA: emerging roles in cancer

YN Han, Y Li, SQ Xia, YY Zhang, JH Zheng… - Cellular Physiology and …, 2018 - karger.com
P-Element induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a type of noncoding
RNAs (ncRNAs) and interact with PIWI proteins. piRNAs were primarily described in the …

[HTML][HTML] The emerging role of the piRNA/piwi complex in cancer

Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

PIWI-interacting RNAs: critical roles and therapeutic targets in cancer

J Zhou, H Xie, J Liu, R Huang, Y Xiang, D Tian, E Bian - Cancer Letters, 2023 - Elsevier
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a novel class of small
regulatory RNAs (approximately 24–31 nucleotides in length) that often bind to members of …

[HTML][HTML] The biogenesis and biological function of PIWI-interacting RNA in cancer

S Chen, S Ben, J Xin, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …

The emerging roles of PIWI-interacting RNA in human cancers

Y Yu, J Xiao, SS Hann - Cancer Management and Research, 2019 - Taylor & Francis
PIWI-interacting RNAs (piRNAs) are a type of non-coding RNAs that interact with PIWI
proteins, which are members of the argonaute family. Originally described in the germline …

[HTML][HTML] Piwi-interacting RNAs in cancer: emerging functions and clinical utility

KW Ng, C Anderson, EA Marshall, BC Minatel… - Molecular cancer, 2016 - Springer
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …

Piwi-interacting RNAs (piRNAs) and cancer: Emerging biological concepts and potential clinical implications

W Weng, H Li, A Goel - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
Piwi-interacting RNAs (piRNAs) are a very recently discovered class of small non-coding
RNAs (ncRNAs), with approximately 20,000 piRNA genes already identified within the …

[HTML][HTML] The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers

Q Zhang, Y Zhu, X Cao, W Tan, J Yu, Y Lu, R Kang… - Molecular Cancer, 2023 - Springer
PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are
significant in development and reproduction of organisms. Recently, emerging evidences …

The role of piRNA and its potential clinical implications in cancer

CB Assumpção, DQ Calcagno, TMT Araújo… - …, 2015 - Taylor & Francis
Epigenetic mechanisms work in an orchestrated fashion to control gene expression in both
homeostasis and diseases. Among small noncoding RNAs, piRNAs seem to meet the …