Treatment and outcome of hemorrhagic transformation after intravenous alteplase in acute ischemic stroke: a scientific statement for healthcare professionals from the …

S Yaghi, JZ Willey, B Cucchiara, JN Goldstein… - Stroke, 2017 - Am Heart Assoc
Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of
intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on …

Symptomatic intracerebral hemorrhage in acute ischemic stroke after thrombolysis with intravenous recombinant tissue plasminogen activator: a review of natural …

S Yaghi, A Eisenberger, JZ Willey - JAMA neurology, 2014 - jamanetwork.com
Importance Intravenous thrombolysis remains the mainstay treatment for acute ischemic
stroke. One of the most feared complications of the treatment is thrombolysis-related …

Management of thrombolysis-associated symptomatic intracerebral hemorrhage

JN Goldstein, M Marrero, S Masrur, M Pervez… - Archives of …, 2010 - jamanetwork.com
Background Symptomatic intracerebral hemorrhage (sICH) is the most devastating
complication of thrombolytic therapy for acute stroke. It is not clear whether patients with …

Symptomatic intracranial hemorrhage following intravenous thrombolysis for acute ischemic stroke: a critical review of case definitions

RCS Seet, AA Rabinstein - Cerebrovascular Diseases, 2012 - karger.com
Background: Symptomatic intracranial hemorrhage (SICH) is a devastating complication of
intravenous thrombolysis treatment that is associated with high mortality. Clinical trials …

Safety and efficacy of alteplase in the treatment of acute ischemic stroke

G Micieli, S Marcheselli, PA Tosi - Vascular health and risk …, 2009 - Taylor & Francis
After publication of the results of the National Institute of Neurological Disorders and Stroke
study, the application of intravenous thrombolysis for ischemic stroke was launched and has …

Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke: a statement for healthcare professionals from the …

BM Demaerschalk, DO Kleindorfer, OM Adeoye… - Stroke, 2016 - Am Heart Assoc
Purpose—To critically review and evaluate the science behind individual eligibility criteria
(indication/inclusion and contraindications/exclusion criteria) for intravenous recombinant …

Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

W Hacke, M Kaste, E Bluhmki, M Brozman… - New England journal …, 2008 - Mass Medical Soc
Background Intravenous thrombolysis with alteplase is the only approved treatment for acute
ischemic stroke, but its efficacy and safety when administered more than 3 hours after the …

Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) …

M Mazya, JA Egido, GA Ford, KR Lees, R Mikulik… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Symptomatic intracerebral hemorrhage (SICH) is a serious
complication in patients with acute ischemic stroke treated with intravenous thrombolysis …

Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors

MG Lansberg, GW Albers, CAC Wijman - Cerebrovascular diseases, 2007 - karger.com
Background: Symptomatic intracerebral hemorrhage (SICH) following thrombolytic therapy
for acute ischemic stroke is associated with a high rate of morbidity and mortality …

Treatment and outcome of thrombolysis-related hemorrhage: a multicenter retrospective study

S Yaghi, AK Boehme, J Dibu, CRL Guerrero… - JAMA …, 2015 - jamanetwork.com
Importance Treatments for symptomatic intracerebral hemorrhage (sICH) are based on
expert opinion, with limited data available on efficacy. Objective To better understand the …