Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis

CR Esther Jr, G Boysen, BM Olsen… - … of Physiology-Lung …, 2009 - journals.physiology.org
Exhaled breath condensate (EBC) analyses promise simple and noninvasive methods to
measure airway biomarkers but pose considerable methodological challenges. We utilized …

A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate

CR Esther Jr, HM Jasin, LB Collins… - … Journal Devoted to …, 2008 - Wiley Online Library
Exhaled breath condensate (EBC) collection is a simple and non‐invasive method to
sample airway secretions, but analysis is limited by extensive and variable dilution of airway …

Exhaled breath condensate purines correlate with lung function in infants and preschoolers

K Patel, SD Davis, R Johnson… - Pediatric …, 2013 - Wiley Online Library
Rationale Although airway inflammation begins early in life in children with chronic
respiratory diseases, current methods to assess this inflammation are invasive and entail …

Exhaled breath condensate adenosine tracks lung function changes in cystic fibrosis

CR Esther Jr, BM Olsen, FC Lin… - American Journal of …, 2013 - journals.physiology.org
Measurement of exhaled breath condensate (EBC) biomarkers offers a noninvasive means
to assess airway disease, but the ability of EBC biomarkers to track longitudinal changes in …

Elevated airway purines in COPD

CR Esther Jr, AL Lazaar, E Bordonali, B Qaqish… - Chest, 2011 - Elsevier
Background Adenosine and related purines have established roles in inflammation, and
elevated airway concentrations are predicted in patients with COPD. However, accurate …

[HTML][HTML] Determining the presence of asthma-related molecules and salivary contamination in exhaled breath condensate

C Cruickshank-Quinn, M Armstrong, R Powell… - Respiratory …, 2017 - Springer
Background Researchers investigating lung diseases, such as asthma, have questioned
whether certain compounds previously reported in exhaled breath condensate (EBC) …

Bioanalysis of underivatized amino acids in non-invasive exhaled breath condensate samples using liquid chromatography coupled with tandem mass spectrometry

L Konieczna, M Pyszka, M Okońska… - … of Chromatography A, 2018 - Elsevier
Exhaled breath condensate (EBC) is receiving increased attention as a novel, entirely non-
invasive technique for collecting biomarker samples. This increased attention is due to the …

Exhaled breath condensate: a promising source for biomarkers of lung disease

Y Liang, SM Yeligar, LAS Brown - The Scientific World Journal, 2012 - Wiley Online Library
Exhaled breath condensate (EBC) has been increasingly studied as a noninvasive research
method for sampling the alveolar and airway space and is recognized as a promising source …

Biomarkers in exhaled breath condensate: a review of collection, processing and analysis

NM Grob, M Aytekin, RA Dweik - Journal of breath research, 2008 - iopscience.iop.org
Exhaled breath condensate (EBC) is a potential rich source for countless biomarkers that
can provide valuable information about respiratory as well as systemic diseases. EBC has …

Exhaled breath condensate: methodological recommendations and unresolved questions

I Horváth, J Hunt, PJ Barnes - European Respiratory Journal, 2005 - Eur Respiratory Soc
Collection of exhaled breath condensate (EBC) is a noninvasive method for obtaining
samples from the lungs. EBC contains large number of mediators including adenosine …