Metabolomics in cancer biomarker discovery: current trends and future perspectives

EG Armitage, C Barbas - Journal of pharmaceutical and biomedical …, 2014 - Elsevier
Cancer is one of the most devastating human diseases that causes a vast number of
mortalities worldwide each year. Cancer research is one of the largest fields in the life …

Emerging field of metabolomics: big promise for cancer biomarker identification and drug discovery

S Patel, S Ahmed - Journal of pharmaceutical and biomedical analysis, 2015 - Elsevier
Most cancers are lethal and metabolic alterations are considered a hallmark of this deadly
disease. Genomics and proteomics have contributed vastly to understand cancer biology …

The applications of metabolomics in the molecular diagnostics of cancer

PK Cheung, MH Ma, HF Tse, KF Yeung… - Expert review of …, 2019 - Taylor & Francis
Introduction: Metabolomics, the study of metabolites, is a promising research field for
cancers. The metabolic pathway in a tumor cell is different from a normal tissue cell. There …

Metabolomics in cancer: a bench-to-bedside intersection

WM Claudino, PH Goncalves, A di Leo… - Critical reviews in …, 2012 - Elsevier
The field of oncology is a rapidly evolving science mostly due to extensive basic,
translational and clinical research which have provided more insights into the tumor biology …

[HTML][HTML] Applications of metabolomics in cancer research

KA Vermeersch, MP Styczynski - Journal of carcinogenesis, 2013 - ncbi.nlm.nih.gov
The first discovery of metabolic changes in cancer occurred almost a century ago. While the
genetic underpinnings of cancer have dominated its study since then, altered metabolism …

Metabolomics analysis for biomarker discovery: advances and challenges

MS Monteiro, M Carvalho, ML Bastos… - Current medicinal …, 2013 - ingentaconnect.com
Over the last decades there has been a change in biomedical research with the search for
single genes, transcripts, proteins, or metabolites being substituted by the coverage of the …

Applications of metabolomics in cancer studies

EG Armitage, M Ciborowski - Metabolomics: From fundamentals to clinical …, 2017 - Springer
Since the start of metabolomics as a field of research, the number of studies related to
cancer has grown to such an extent that cancer metabolomics now represents its own …

Metabolomics in diagnosis and biomarker discovery of colorectal cancer

A Zhang, H Sun, G Yan, P Wang, Y Han, X Wang - Cancer letters, 2014 - Elsevier
Colorectal cancer (CRC), a major public health concern, is the second leading cause of
cancer death in developed countries. There is a need for better preventive strategies to …

Clinical applications of metabolomics in oncology: a review

JL Spratlin, NJ Serkova, SG Eckhardt - Clinical cancer research, 2009 - AACR
Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …

Challenges and opportunities in cancer metabolomics

A Kumar, BB Misra - Proteomics, 2019 - Wiley Online Library
Challenges in metabolomics for a given spectrum of disease are more or less comparable,
ranging from the accurate measurement of metabolite abundance, compound annotation …