Investigations of the reactivity, stability and biological activity of halido (NHC) gold (I) complexes

SK Goetzfried, P Kapitza, CM Gallati, A Nindl… - Dalton …, 2022 - pubs.rsc.org
The significance of the halido ligand (Cl−, Br−, I−) in halido [3-ethyl-4-phenyl-5-(2-
methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2H-imidazol-2-ylidene] gold (I) complexes (2–4) …

Reaction Behavior of [1,3-Diethyl-4,5-diphenyl-1H-imidazol-2-ylidene] Containing Gold(I/III) Complexes against Ingredients of the Cell Culture Medium and the …

P Kapitza, A Scherfler, S Salcher… - Journal of Medicinal …, 2023 - ACS Publications
The reactivities of halido [1, 3-diethyl-4, 5-diphenyl-1 H-imidazol-2-ylidene] gold (I)(chlorido
(5), bromido (6), iodido (7)), bis [1, 3-diethyl-4, 5-diphenyl-1 H-imidazol-2-ylidene] gold (I)(8) …

Synthesis, characterization and biological activity of bromido [3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2 H-imidazol-2-ylidene] gold (i) complexes

CM Gallati, SK Goetzfried, M Ausserer… - Dalton …, 2020 - pubs.rsc.org
Bromido [3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2H-imidazol-2-
ylidene] gold (I) complexes (8a–h) with methoxy, methyl and fluorine substituents at different …

Gold (III) derivatives in colon cancer treatment

A Gurba, P Taciak, M Sacharczuk… - International Journal of …, 2022 - mdpi.com
Cancer is one of the leading causes of morbidity and mortality worldwide. Colorectal cancer
(CRC) is the third most frequently diagnosed cancer in men and the second in women …

Gold (I) complexes with a quinazoline carboxamide alkynyl ligand: Synthesis, cytotoxicity, and mechanistic studies

L Tabrizi, WS Yang, C Chintha… - European Journal of …, 2021 - Wiley Online Library
A series of gold (I) complexes with the general formula [Au (L2)(L′)](L2= 4‐phenyl‐N‐(prop‐
2‐yn‐1‐yl) quinazoline‐2‐carboxamide, L′= PPh3 (triphenylphosphine), 1; TPA (1, 3, 5 …

Synthesis, characterization and biological activity of bis [3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2 H-imidazol-2-ylidene] gold (i) complexes

CM Gallati, SK Goetzfried, A Ortmeier, J Sagasser… - Dalton …, 2021 - pubs.rsc.org
A series of bis [3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2H-imidazol-2-
ylidene] gold (I) complexes (2a–f) containing methyl, fluoro or methoxy substituents at …

Characterization of hydrophilic gold (I) N-heterocyclic carbene (NHC) complexes as potent TrxR inhibitors using biochemical and mass spectrometric approaches

O Karaca, V Scalcon, SM Meier-Menches… - Inorganic …, 2017 - ACS Publications
We report here on the synthesis of a series of mono-and dinuclear gold (I) complexes
exhibiting sulfonated bis (NHC) ligands and novel hydroxylated mono (NHC) Au (I) …

Pharmacomodulation on Gold-NHC complexes for anticancer applications–is lipophilicity the key point?

C Zhang, ML Maddelein, RWY Sun, H Gornitzka… - European Journal of …, 2018 - Elsevier
A series of four new mononuclear cationic gold (I) complexes containing nitrogen
functionalized N-heterocyclic carbenes (NHCs) was synthesized and fully characterized by …

Synthesis, structural characterization, solution behavior, and in vitro antiproliferative properties of a series of gold complexes with 2-(2′-pyridyl) benzimidazole as …

M Serratrice, MA Cinellu, L Maiore, M Pilo… - Inorganic …, 2012 - ACS Publications
A variety of gold (III) and gold (I) derivatives of 2-(2′-pyridyl) benzimidazole (pbiH) were
synthesized and fully characterized and their antiproliferative properties evaluated in a …

Synthesis, characterization, and in vitro studies of bis [1, 3-diethyl-4, 5-diarylimidazol-2-ylidene] gold (I/III) complexes

W Liu, K Bensdorf, M Proetto… - Journal of medicinal …, 2012 - ACS Publications
Cationic bis [1, 3-diethyl-4, 5-diarylimidazol-2-ylidene] gold (I) complexes with 4-OCH3 or 4-
F substituents in the aromatic rings and Br–(3a, b) or BF4–(7a, b) counterions were …