The uterine cervix undergoes a complex remodelling process during pregnancy,
characterized by dramatic changes in both extracellular matrix (ECM) structure and …

Appropriate mechanical function of the uterine cervix is critical for maintaining a pregnancy
to term so that the fetus can develop fully. At the end of pregnancy, however, the cervix must …

A well-timed modification of both the collagen and elastic fiber network in the cervix during
pregnancy accompanies the evolution of tissue mechanical parameters that are key to a …

Major clinical challenges for obstetricians and neonatologists result from early cervix
remodeling and preterm birth. Complications related to cervix remodeling or delivery …

Cervical remodeling during pregnancy and parturition is a single progressive process that
can be loosely divided into four overlapping phases termed softening, ripening …

Through pregnancy the cervix must simultaneously remain competent for pregnancy
maintenance and yet become progressively compliant to ensure on time parturition. Cervical …

The cervix acts as a dynamic barrier between the uterus and vagina, retaining the fetus
during pregnancy and allowing birth at term. Critical to this function, the physical properties …

An appropriately timed cervical remodeling process is critical for a healthy delivery, yet little
is known about the material property changes of the cervix in pregnancy because obtaining …

Proper cervical function is essential for a normal pregnancy and birth to occur.
Understanding the mechanisms that take place in normal pregnancy will allow a better …

In normal pregnancy, the cervix maintains its shape during a period of substantial fetal and
uterine growth. Hence, maintenance of biomechanical integrity is an important aspect of …