Pushing the boundaries of neuroimaging with optoacoustics
With the central ability to visualize a variety of endogenous chromophores and biomarkers
or exogenous contrast agents, optoacoustic (photoacoustic) imaging empowers new …
or exogenous contrast agents, optoacoustic (photoacoustic) imaging empowers new …
Multi-scale optoacoustic molecular imaging of brain diseases
The ability to non-invasively visualize endogenous chromophores and exogenous probes
and sensors across the entire rodent brain with the high spatial and temporal resolution has …
and sensors across the entire rodent brain with the high spatial and temporal resolution has …
Advanced optoacoustic methods for multiscale imaging of in vivo dynamics
XL Deán-Ben, S Gottschalk, B Mc Larney… - Chemical Society …, 2017 - pubs.rsc.org
Visualization of dynamic functional and molecular events in an unperturbed in vivo
environment is essential for understanding the complex biology of living organisms and of …
environment is essential for understanding the complex biology of living organisms and of …
Spatial and spectral mapping and decomposition of neural dynamics and organization of the mouse brain with multispectral optoacoustic tomography
I Olefir, A Ghazaryan, H Yang… - Cell Reports, 2019 - cell.com
In traditional optical imaging, limited light penetration constrains high-resolution
interrogation to tissue surfaces. Optoacoustic imaging combines the superb contrast of …
interrogation to tissue surfaces. Optoacoustic imaging combines the superb contrast of …
Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain
S Gottschalk, O Degtyaruk, B Mc Larney… - Nature biomedical …, 2019 - nature.com
Efforts to scale neuroimaging towards the direct visualization of mammalian brain-wide
neuronal activity have faced major challenges. Although high-resolution optical imaging of …
neuronal activity have faced major challenges. Although high-resolution optical imaging of …
Universal hand-held three-dimensional optoacoustic imaging probe for deep tissue human angiography and functional preclinical studies in real time
X Deán-Ben, TF Fehm, D Razansky - JoVE (Journal of Visualized …, 2014 - jove.com
The exclusive combination of high optical contrast and excellent spatial resolution makes
optoacoustics (photoacoustics) ideal for simultaneously attaining anatomical, functional and …
optoacoustics (photoacoustics) ideal for simultaneously attaining anatomical, functional and …
Functional optoacoustic neuro-tomography for scalable whole-brain monitoring of calcium indicators
XL Deán-Ben, G Sela, A Lauri, M Kneipp… - Light: Science & …, 2016 - nature.com
Non-invasive observation of spatiotemporal activity of large neural populations distributed
over entire brains is a longstanding goal of neuroscience. We developed a volumetric …
over entire brains is a longstanding goal of neuroscience. We developed a volumetric …
Molecular imaging probes for multi-spectral optoacoustic tomography
Multi-Spectral Optoacoustic Tomography (MSOT) merges the power of high-resolution
imaging at tissue depths of several millimeters to centimeters with the advantages of optical …
imaging at tissue depths of several millimeters to centimeters with the advantages of optical …
Photoacoustic neuroimaging-perspectives on a maturing imaging technique and its applications in neuroscience
SV Bodea, GG Westmeyer - Frontiers in Neuroscience, 2021 - frontiersin.org
A prominent goal of neuroscience is to improve our understanding of how brain structure
and activity interact to produce perception, emotion, behavior, and cognition. The brain's …
and activity interact to produce perception, emotion, behavior, and cognition. The brain's …
Toward whole-brain in vivo optoacoustic angiography of rodents: modeling and experimental observations
P Subochev, E Smolina, E Sergeeva… - Biomedical optics …, 2020 - opg.optica.org
Cerebrovascular imaging of rodents is one of the trending applications of optoacoustics
aimed at studying brain activity and pathology. Imaging of deep brain structures is often …
aimed at studying brain activity and pathology. Imaging of deep brain structures is often …