Simple Summary Colorectal cancer (CRC) is an emerging public health problem and the
second leading cause of death worldwide, with a significant socioeconomic impact in …

Colorectal cancer (CRC) was ranked third in morbidity and mortality in the United States in
2013. Although substantial progress has been made in surgical techniques and …

Wnt/β‐catenin pathway is one of the main/frequent dysregulated pathways in several tumor
types, including colon cancer. Aberrant activation of this pathway is associated with cell …

Colorectal cancer (CRC) is one of the most common malignant tumor types occurring in the
digestive system. The incidence of CRC has exhibits yearly increases and the mortality rate …

Colorectal cancer (CRC) has become a global public health problem because of its high
incidence and mortality rate worldwide. The previous clinical treatment for CRC mainly …

Colorectal cancer (CRC) is the third most common cause of cancer‐related death worldwide
in terms of both its rates of incidence and mortality. Due to serious side effects associated …

The canonical Wnt pathway is one of the key cellular signaling cascades that regulates, via
the transcriptional co-activator β-catenin, numerous embryogenic developmental processes …

The Wnt/β-catenin signaling pathway, including canonical or noncanonical pathway, is a
highly conserved pathway which can regulate cell proliferation, migration, differentiation …

Aberrant Wnt/β-catenin signaling has often been reported in different cancers, particularly
colorectal cancer (CRC), and this signaling cascade is central to carcinogenesis …

Colorectal cancer (CRC) represents one of the most common cancers worldwide, with a
high mortality rate despite the decreasing incidence and new diagnostic and therapeutic …