The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury.
Acute myocardial infarction stands as a prominent cause of morbidity and mortality
worldwide 1-6. Clinical studies have demonstrated that the severity of cardiac injury …
worldwide 1-6. Clinical studies have demonstrated that the severity of cardiac injury …
The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
H Eltzschig, W Ruan, T Li, J Lee, IH Bang, W Deng… - europepmc.org
Acute myocardial infarction stands as a prominent cause of morbidity and mortality
worldwide 1-6. Clinical studies have demonstrated that the severity of cardiac injury …
worldwide 1-6. Clinical studies have demonstrated that the severity of cardiac injury …
[HTML][HTML] The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
Acute myocardial infarction stands as a prominent cause of morbidity and mortality
worldwide 1–6. Clinical studies have demonstrated that the severity of cardiac injury …
worldwide 1–6. Clinical studies have demonstrated that the severity of cardiac injury …
[HTML][HTML] Circadian biology, cardiovascular function and disease
N Chong, P Campagnolo - Frontiers in pharmacology, 2023 - frontiersin.org
Cardiovascular disease (CVD) are complex multi-factorial disorders that constitutes the
leading cause of morbidity and mortality worldwide (Roth et al., 2020). Homeostatic heart …
leading cause of morbidity and mortality worldwide (Roth et al., 2020). Homeostatic heart …
Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart
ME Young, RA Brewer… - Journal of biological …, 2014 - journals.sagepub.com
Circadian clocks are cell autonomous, transcriptionally based, molecular mechanisms that
confer the selective advantage of anticipation, enabling cells/organs to respond to …
confer the selective advantage of anticipation, enabling cells/organs to respond to …
[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: Differential effects of REV-ERBα/β agonism on cardiac gene expression, metabolism, and …
Cell-autonomous circadian clocks have emerged as temporal orchestrators of numerous
biological processes. For example, the cardiomyocyte circadian clock modulates …
biological processes. For example, the cardiomyocyte circadian clock modulates …
Differential effects of REV-ERBα/β agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption
Cell-autonomous circadian clocks have emerged as temporal orchestrators of numerous
biological processes. For example, the cardiomyocyte circadian clock modulates …
biological processes. For example, the cardiomyocyte circadian clock modulates …
Circadian-hypoxia link and its potential for treatment of cardiovascular disease
CM Bartman, T Eckle - Current pharmaceutical design, 2019 - ingentaconnect.com
Throughout the evolutionary time, all organisms and species on Earth evolved with an
adaptation to consistent oscillations of sunlight and darkness, now recognized as 'circadian …
adaptation to consistent oscillations of sunlight and darkness, now recognized as 'circadian …
[HTML][HTML] Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury
Z Qiu, H Ming, S Lei, B Zhou, B Zhao, Y Yu, R Xue… - Cell death & …, 2021 - nature.com
The circadian clock is closely related to the development of diabetes mellitus and
cardiovascular disease, and disruption of the circadian clock exacerbates myocardial …
cardiovascular disease, and disruption of the circadian clock exacerbates myocardial …
Influence of circadian rhythms on myocardial infarction
S Fournier, AT Beggah, S Cook, O Muller - Revue medicale suisse, 2014 - europepmc.org
Myocardial infarction is one of the most important causes of mortality and its incidence
exhibits a significant circadian pattern with a peak of maximum frequency between 10 am …
exhibits a significant circadian pattern with a peak of maximum frequency between 10 am …