Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

Progress toward the development of efficacious therapies for Alzheimer's disease (AD) is
halted by a lack of understanding early underlying pathological mechanisms. Systems …

Alzheimer's disease is a complex neurodegenerative disorder characterized by a multi-
factorial etiology, not completely understood to date. In this context, the application of …

Although the pathogenesis of Alzheimer's disease (AD) is still not fully understood, it is
acknowledged that intervention should be made at the early stage. Therefore, identifying …

The pathophysiological changes associated with Alzheimer's Disease (AD) begin decades
before the emergence of clinical symptoms. Understanding the early mechanisms …

The rapid increase in the older population has made age‐related diseases like Alzheimer's
disease (AD) a global concern. Given that there is still no cure for this neurodegenerative …

Alzheimer's disease (AD) is an aging-related neurodegenerative disease, leading to the
progressive loss of memory and other cognitive functions. As there is still no cure for AD, the …

With an increase in aging populations worldwide, age-related diseases such as Alzheimer's
disease (AD) have become a global concern. At present, a cure for neurodegenerative …

Alzheimer's disease (AD) is a complex disease driven mainly by neuronal loss due to
accumulation of intracellular neurofibrillary tangles and amyloid β aggregates in the brain …

Background The metabolic basis of Alzheimer disease (AD) is poorly understood, and the
relationships between systemic abnormalities in metabolism and AD pathogenesis are …