Imaging Somatostatin Positive Tumors with Tyr3-Octreotate/Octreotide Conjugated to Desferrioxamine B Squaramide Radiolabeled with either Zirconium-89 or …
Radiolabeled derivatives of Tyr3-octreotide and Tyr3-octreotate, synthetic analogues of the
peptide hormone somatostatin, can be used for positron emission tomography (PET) …
peptide hormone somatostatin, can be used for positron emission tomography (PET) …
NODAGATOC, a New Chelator-Coupled Somatostatin Analogue Labeled with [67/68Ga] and [111In] for SPECT, PET, and Targeted Therapeutic Applications of …
KP Eisenwiener, MIM Prata, I Buschmann… - Bioconjugate …, 2002 - ACS Publications
A monoreactive NOTA (1, 4, 7-triazacyclononane-1, 4, 7-triacetic acid) derived prochelator
(1-(1-carboxy-3-carbo-tert-butoxypropyl)-4, 7-(carbo-tert-butoxymethyl)-1, 4, 7 …
(1-(1-carboxy-3-carbo-tert-butoxypropyl)-4, 7-(carbo-tert-butoxymethyl)-1, 4, 7 …
Metal‐Ion‐Dependent Biological Properties of a Chelator‐Derived Somatostatin Analogue for Tumour Targeting
A Heppeler, JP André, I Buschmann… - … A European Journal, 2008 - Wiley Online Library
Somatostatin‐based radioligands have been shown to have sensitive imaging properties for
neuroendocrine tumours and their metastases. The potential of [55Co (dotatoc)](dotatoc= 4 …
neuroendocrine tumours and their metastases. The potential of [55Co (dotatoc)](dotatoc= 4 …
Positron Emission Tomographic Imaging of Copper 64– and Gallium 68–Labeled Chelator Conjugates of the Somatostatin Agonist Tyr3-Octreotate
The bifunctional chelator and radiometal have been shown to have a direct effect on the
pharmacokinetics of somatostatin receptor (SSTR)-targeted imaging agents. We evaluated …
pharmacokinetics of somatostatin receptor (SSTR)-targeted imaging agents. We evaluated …
Synthesis, radiolabeling, and preclinical evaluation of a new octreotide analog for somatostatin receptor‐positive tumor scintigraphy
K De, A Bhowmik, A Behera, I Banerjee… - Journal of Peptide …, 2012 - Wiley Online Library
Radiolabeled somatostatin analogs have become powerful tools in the diagnosis and
staging of neuroendocrine tumors, which express somatostatin receptors. The aim of this …
staging of neuroendocrine tumors, which express somatostatin receptors. The aim of this …
Radiosynthesis and Preclinical Evaluation of 18F-Fluoroglycosylated Octreotate for Somatostatin Receptor Imaging
S Maschauer, M Heilmann, C Wängler… - Bioconjugate …, 2016 - ACS Publications
Short synthetic octapeptide analogs derived from the native somatostatin peptides SST-14
and SST-28, namely, octreotate (TATE) or octreotide (TOC), bind with high affinity to …
and SST-28, namely, octreotate (TATE) or octreotide (TOC), bind with high affinity to …
Preparation and Biological Evaluation of 64Cu Labeled Tyr3-Octreotate Using a Phosphonic Acid-Based Cross-Bridged Macrocyclic Chelator
Y Guo, R Ferdani, CJ Anderson - Bioconjugate chemistry, 2012 - ACS Publications
Somatostatin receptors (SSTr) are overexpressed in a wide range of neuroendocrine
tumors, making them excellent targets for nuclear imaging and therapy, and radiolabeled …
tumors, making them excellent targets for nuclear imaging and therapy, and radiolabeled …
Effects of Chelator Modifications on 68Ga-Labeled [Tyr3]Octreotide Conjugates
Purpose Somatostatin receptors (SSTR) have been reported as promising targets for
imaging agents for cancer. Recently, 68 Ga-DOTATOC-based PET imaging has been used …
imaging agents for cancer. Recently, 68 Ga-DOTATOC-based PET imaging has been used …
Preparation and Biological Evaluation of [99mTc/EDDA/Tricine/HYNIC0, BzThi3]-Octreotide for Somatostatin Receptor-Positive Tumor Imaging
M Erfani, M Shafiei, M Mazidi… - Cancer Biotherapy and …, 2013 - liebertpub.com
Somatostatin-derived analogues play an important role in the diagnosis and treatment of
neuroendocrine tumors. The aim of this study was to evaluate a new somatostatin analogue …
neuroendocrine tumors. The aim of this study was to evaluate a new somatostatin analogue …
Ga-66 labeled somatostatin analogue DOTA-DPhe1-Tyr3-octreotide as a potential agent for positron emission tomography imaging and receptor mediated internal …
Ö Ugur, PJ Kothari, RD Finn, P Zanzonico… - Nuclear medicine and …, 2002 - Elsevier
Radionuclide labeled somatostatin analogues selectively target somatostatin receptor
(SSTR)-expressing tumors as a basis for diagnosis and treatment of these tumors. Recently …
(SSTR)-expressing tumors as a basis for diagnosis and treatment of these tumors. Recently …
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