Cationic switchable lipids belong to the class of stimuli-responsive materials. When
incorporated in lipid nanoparticles (LNP), switchable LNP promote pH-triggered delivery of …

A pH-sensitive molecular switch able to change its conformation upon protonation at
endosomal pH values is embedded into the structure of cationic lipidoid materials, thus …

The aforementioned characteristics of liposomes make them an important mimetic model of
biomembranes that can be used in various pharmacological and biophysical studies related …

Drug resistance, inefficient cellular uptake and the subservient drug release to increase the
intracellular drug concentration inside the tumor cells are the key reasons for low therapeutic …

Enhanced tumor cellular internalization and triggered drug release are two main concerns in
the development of nanoparticles for antitumor drug delivery. In this article, a new kind of …

To overcome the major obstacle of successful cancer chemotherapy, multidrug resistance
(MDR), we prepared lipid-shell and polymer-core nanoparticles (LPNPs) to co-deliver an …

Background: Liposomes are vesicular carriers which possess aqueous core entrapped
within the lipid bilayer. These are carriers of choice because of biocompatible and …

Stimuli-responsive lipid-bioactive conjugate-based nanocarriers are a revolutionary
approach in biomaterial applications. These advanced nanosystems can remarkably adapt …

Nanocarrier systems are widely used for drug delivery applications, but limitations such as
the use of synthetic surfactants, leakage of toxic drugs, and a poor encapsulation capacity …

In order to obtain nanocarriers suitable for the delivery of drugs in the treatment of cancer,
pH-responsive nanovesicles capable of facilitating fusion (fusogenic nanovesicles) were …