Conspectus Molecular association of proteins with nucleic acids is required for many
biological processes essential to life. Electrostatic interactions via ion pairs (salt bridges) of …

Ions surround nucleic acids in what is referred to as an ion atmosphere. As a result, the
folding and dynamics of RNA and DNA and their complexes with proteins and with each …

The ion atmosphere is a critical structural, dynamic, and energetic component of nucleic
acids that profoundly affects their interactions with proteins and ligands. Experimental …

The observed salt dependence of charged ligand binding to polyelectrolytes, such as
proteins to DNA or antithrombin to heparin, is often interpreted by means of the “oligolysine …

Intermolecular ion pairs (salt bridges) are crucial for protein–DNA association. For two
protein–DNA complexes, we demonstrate that the ion pairs of protein side-chain NH3+ and …

Ion pairing is one of the most fundamental chemical interactions and is essential for
molecular recognition by biological macromolecules. From an experimental standpoint, very …

Electrostatics are central to all aspects of nucleic acid behavior, including their folding,
condensation, and binding to other molecules, and the energetics of these processes are …

The concept of “ion atmosphere” is prevalent in both theoretical and experimental studies of
nucleic acid systems, yet the spatial arrangement and the composition of ions in the ion …

The composition of the ion atmosphere surrounding nucleic acids affects their folding,
condensation and binding to other molecules. It is thus of fundamental importance to gain …

Nucleic acids are highly charged polyelectrolytes. Their interactions with counterions are of
great importance for their structural stability, conformational behaviour and biological …