The effect of chronic hypobaric hypoxia (28 days, 455 Torr) on the organization of brain
vessels was studied in Balb/c mice. In comparison to age-matched controls kept at sea level …

We performed 3-dimensional studies of vascular casts of the microvasculature of the
cerebral cortex of rats that were exposed to three weeks of hypobaric hypoxia and of control …

The effects of moderate and severe hypoxia on quantitative regional morphometric indexes
of the total and perfused arteriolar and capillary network were studied in the rat brain to …

To estimate the magnitude of hyperemia necessary to support oxidative metabolism in the
cerebral cortex during functional activation, a mathematical model of O2 transport from …

The postulation that hypoxia increases local cerebral blood flow (lCBF) mainly by perfusing
more capillaries (the capillary recruitment hypothesis) was tested in awake adult male …

The blood vessels in the brains of adult rats subjected to chronic normobaric hypoxia and
control animals housed under normoxic conditions were morphometrically studied. Hypoxic …

Rats were exposed to hypobaric hypoxia (0.5 atm) for up to 3 wk. Hypoxic rats failed to gain
weight but maintained normal brain water and ion content. Blood hematocrit was increased …

Exposure to mild hypoxia elicits a characteristic cerebrovascular response in mammals,
including humans. Initially, cerebral blood flow (CBF) increases as much as twofold. The …

Objective: Simulations of oxygen delivery by a three‐dimensional network of microvessels in
rat cerebral cortex were used to examine how the distribution of partial pressure of oxygen …

A compartmental model is formulated for oxygen transport in the cerebrovascular bed of the
brain. The model considers the arteriolar, capillary and venular vessels. The vascular bed is …