The Insulin-like growth factor 2 (Igf2) and H19 genes are imprinted, resulting in silencing of
the maternal and paternal alleles, respectively. This event is dependent upon an imprinted …

The expression of the insulin-like growth factor 2 (Igf2) and H19 genes is imprinted.
Although these neighbouring genes share an enhancer, H19 is expressed only from the …

Genomic imprinting relies on establishing and maintaining the parental-specific methylation
of DNA elements that control the differential expression of maternal and paternal alleles …

Gametic imprinting is a developmental process that induces parental-specific expression or
repression of autosomal and X-chromosome-linked genes,. The mouse Igf2r gene …

Imprinted genes are expressed from only one of the parental alleles and are marked
epigenetically by DNA methylation and histone modifications,,,,. The paternally expressed …

Imprinted expression at the H19-Igf2 locus depends on a differentially methylated domain
(DMD) that acts both as a maternal-specific, methylation-sensitive insulator and as a …

In mammals, a subset of genes inherit gametic marks that establish parent of origin-
dependent expression patterns in the soma ([1] and references therein). The currently most …

THE paternal and maternal genomes are not equivalent and both are required for
mammalian development1, 2. The difference between the parental genomes is believed to …

The mouse Igf2 and H19 genes lie 70-kb apart on chromosome 7 and are reciprocally
imprinted. Two regulatory regions are important for their parental allele-spedfic expression …

Genomic imprinting is the process in mammals by which gamete-specific epigenetic
modifications establish the differential expression of the two alleles of a gene. The tightly …