Long-term prognostic value of IgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease
A Imhof, W Koenig, A Jaensch, U Mons, H Brenner… - Atherosclerosis, 2015 - Elsevier
Abstract Background Low concentrations of IgM-phosphorylcholine autoantibodies (IgM-anti-
PC) have been shown to be associated with increased risk of incident cardiovascular …
PC) have been shown to be associated with increased risk of incident cardiovascular …
IgM-phosphorylcholine autoantibodies and outcome in acute coronary syndromes
K Caidahl, M Hartford, T Karlsson, J Herlitz… - International journal of …, 2013 - Elsevier
BACKGROUND: Antibodies against proinflammatory phosphorylcholine (anti-PC) seem to
be protective and reduce morbidity. We sought to determine whether low levels of …
be protective and reduce morbidity. We sought to determine whether low levels of …
[HTML][HTML] Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery …
CA Gleissner, C Erbel, J Haeussler… - Clinical Research in …, 2015 - Springer
Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden
H Grönlund, G Hallmans, JH Jansson… - European Journal of …, 2009 - academic.oup.com
Objective Phosphorylcholine (PC) is one important epitope on oxidized low-density
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized …
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized …
[HTML][HTML] Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial
BJ Geller, JL Mega, DA Morrow, J Guo… - Journal of thrombosis …, 2014 - Springer
Atherogenesis is a complex inflammatory process stemming from the accumulation and
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
Low levels of IgM antibodies against phosphorylcholine—a potential risk marker for ischemic stroke in men
BG Sjöberg, J Su, I Dahlbom, H Grönlund, M Wikström… - Atherosclerosis, 2009 - Elsevier
BACKGROUND: Natural antibodies specific for phosphorylcholine (anti-PC) have been
implicated as protective factors in atherosclerosis. We herein determined the relationship …
implicated as protective factors in atherosclerosis. We herein determined the relationship …
[HTML][HTML] IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with …
R Fiskesund, J Su, I Bulatovic, M Vikström… - Results in …, 2012 - Elsevier
Background We have reported that anti-phosphorylcholine (anti-PC) IgM is a protection
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential …
U de Faire, J Su, X Hua, A Frostegård, M Halldin… - Journal of …, 2010 - Elsevier
OBJECTIVE: We here determine the role of IgM antibodies against phosphorylcholine (anti-
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …
Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men
B Gigante, K Leander, M Vikström, D Baldassarre… - Atherosclerosis, 2014 - Elsevier
Abstract Objective Low levels of IgM anti-phosphorylcholine (anti-PC) increase the risk of
cardiovascular events (CVE). Here we investigate the association of low anti-PC with the …
cardiovascular events (CVE). Here we investigate the association of low anti-PC with the …
Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
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