Development of air-assisted atomization device for the delivery of cells in viscous biological ink prepared with sodium alginate

X Yan, C Wang, Y Ma, Y Wang, F Song… - Review of Scientific …, 2023 - pubs.aip.org
Skin wounds, especially large-area skin trauma, would bring great pain and even fatal risk to
patients. In recent years, local autologous cell transplantation has shown great potential for …

Novel pneumatically assisted atomization device for living cell delivery: application of sprayed mesenchymal stem cells for skin regeneration

L Zhang, X Yan, L An, M Wang, X Xu, Z Ma… - Bio-Design and …, 2021 - Springer
Large cutaneous wounds pose a severe medical problem and may be deadly in cases when
regeneration is impaired. Recently, topical stem cell therapy has been realized as a …

Cell-encapsulating alginate microsized beads using an air-assisted atomization process to obtain a cell-laden hybrid scaffold

S Ahn, GH Kim - Journal of Materials Chemistry B, 2015 - pubs.rsc.org
The air-assisted atomization process is a method for straightforwardly spraying a liquid to
obtain microsized capsules. In this study, we used the atomization process to obtain …

Auto micro atomization delivery of human epidermal organoids improves therapeutic effects for skin wound healing

M Chang, J Liu, B Guo, X Fang, Y Wang… - … in Bioengineering and …, 2020 - frontiersin.org
Severe skin wounds are often associated with large areas of damaged tissue, resulting in
substantial loss of fluids containing electrolytes and proteins. The net result is a vulnerability …

Mammalian cell delivery via aerosol deposition

WS Veazey, KJ Anusavice… - Journal of Biomedical …, 2005 - Wiley Online Library
The objective of this study was to test the hypothesis that bovine dermal fibroblasts can
survive aerosol delivery via an airbrush with mean cell survival rates greater than 50%. This …

The current challenges on spray-based cell delivery to the skin wounds

S Motamedi, A Esfandpour, A Babajani… - … Engineering Part C …, 2021 - liebertpub.com
Cell delivery through spray instruments is a promising and effective method in tissue
engineering and regenerative medicine. It is used for treating different acute and chronic …

Effervescent atomizer as novel cell spray technology to decrease the gas-to-liquid ratio

AL Thiebes, S Klein, J Zingsheim, GH Möller, S Gürzing… - Pharmaceutics, 2022 - mdpi.com
Cell spraying has become a feasible application method for cell therapy and tissue
engineering approaches. Different devices have been used with varying success. Often, twin …

[PDF][PDF] Droplet-born Air Blowing (DAB) technology for the industrialization of dissolving microneedle

JD Kim, JH Bae, HK Kim, DH Jeong - … of the World Congress on Recent …, 2016 - avestia.com
The microneedle mediated drug delivery system has been developed to provide painless
self-administration of highpotency drug with patient friendly manner [1]. Especially …

[HTML][HTML] ATMP-classified, scalable, autologous cell spray for the treatment of skin wounds and assessment of its effects on wound healing clinically and on a molecular …

K Nuutila, S Katayama, A Laitinen, A Siltanen… - burns, 2023 - Elsevier
Background Autologous split-thickness skin grafts (STSGs) are the standard of care for
closure of deep and large burns. However, perforation and extensive fishnet-like expansion …

Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds

A Skardal, D Mack, E Kapetanovic… - Stem cells …, 2012 - academic.oup.com
Stem cells obtained from amniotic fluid show high proliferative capacity in culture and
multilineage differentiation potential. Because of the lack of significant immunogenicity and …