Design and evaluation of a hypoallergenic peptide-based vaccine for Salsola kali allergy

S Tabesh, S Fanuel, MR Fazlollahi… - International …, 2019 - Elsevier
Abstract Background The Salsola kali (S. kali) pollen is one of the most important causes of
allergic rhinitis in the deserts and semi-desert areas. Immunotherapy with allergen extracts …

[HTML][HTML] Designing a T-cell epitope-based vaccine using in silico approaches against the Sal k 1 allergen of Salsola kali plant

MH Shams, SM Sohrabi, R Jafari, A Sheikhian… - Scientific Reports, 2024 - nature.com
Allergens originated from Salsola kali (Russian thistle) pollen grains are one of the most
important sources of aeroallergens causing pollinosis in desert and semi-desert regions. T …

Production of recombinant protein of Salsola kali (Sal k1) pollen allergen in Lactococcus lactis

Z Ghasemi, AR Varasteh, M Moghadam… - Iranian Journal of …, 2018 - ijaai.tums.ac.ir
The Salsola kali pollen is considered the main cause of allergic sensitization in desert and
semi-desert regions. We have constructed recombinant Lactococcus lactis producing Sal k1 …

Expression of the recombinant major allergen of Salsola kali pollen (Sal k 1) and comparison with its low-immunoglobulin E-binding mutant

MA Assarehzadegan, M Sankian, F Jabbari… - Allergology …, 2010 - jstage.jst.go.jp
Background: The inhalation of Salsola kali pollen is an important cause of pollinosis during
summer and early fall throughout desert and semi-desert areas. Sal k 1 has been previously …

Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule

C Colás, S Monzón, M Venturini, A Lezaun - Journal of allergy and clinical …, 2006 - Elsevier
BACKGROUND: The inhalation of Salsola kali pollen is a common cause of respiratory
diseases in Europe and North America. OBJECTIVE: To evaluate the efficacy and safety of a …

Extensive Cross-reactivity Between Salsola kali and Salsola imbricata.

M Al-Ahmad, T Rodriguez-Bouza, N Fakim… - … Allergology & Clinical …, 2017 - europepmc.org
Background There are no studies on cross-reactivity between Salsola kali and Salsola
imbricata pollens. The main goals of the present study were to compare the degree of the …

An alternative allergen: adjuvant formulation potentiates the immunogenicity and reduces allergenicity of a novel subcutaneous immunotherapy product for treatment …

C Rask, L Lund, G Lund, B Heydenreich… - Clinical & …, 2012 - Wiley Online Library
Background Subcutaneous specific immunotherapy (SCIT) has proven sustained clinical
efficacy against allergy. The recommended regimen for SCIT is a gradual updosing over a …

A recombinant Sal k 1 isoform as an alternative to the polymorphic allergen from Salsola kali pollen for allergy diagnosis

S Mas, P Boissy, RI Monsalve… - International archives of …, 2015 - karger.com
Background: The incidence of Amaranthaceae pollen allergy has increased due to the
desertification occurring in many countries. In some regions of Spain, Salsola kali is the …

[HTML][HTML] Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy

M Focke-Tejkl, M Weber, K Niespodziana… - Journal of Allergy and …, 2015 - Elsevier
Background Grass pollen is one of the most important sources of respiratory allergies
worldwide. Objective This study describes the development of a grass pollen allergy vaccine …

[HTML][HTML] Lactobacillus buchneri S-layer as carrier for an Ara h 2-derived peptide for peanut allergen-specific immunotherapy

J Anzengruber, M Bublin, E Bönisch, B Janesch… - Molecular …, 2017 - Elsevier
Peanut allergy is an IgE-mediated severe hypersensitivity disorder. The lack of a treatment
of this potentially fatal allergy has led to intensive research on vaccine development. Here …