Abdominal pain is one of the main symptoms of chronic gastrointestinal disorders including
inflammatory bowel diseases (IBD) and irritable bowel syndrome (IBS). The pathological …

Chronic abdominal pain is the most common gastrointestinal issue and contributes to the
pathophysiology of functional bowel disorders and inflammatory bowel disease. Current …

Background & Aims Chronic abdominal pain is a common symptom of inflammatory bowel
diseases (IBDs). Peripheral and central mechanisms contribute to the transition from acute …

Dr. David Julius and Dr. Ardem Patapoutian for their groundbreaking discoveries of the
transient receptor potential cation channel subfamily V member 1 (TRPV1), the transient …

Visceral hypersensitivity is an important factor underlying abdominal pain in functional
gastrointestinal disorders such as irritable bowel syndrome (IBS) and can result from …

Irritable bowel syndrome and inflammatory bowel disease are major forms of chronic
visceral pain, which affect over 15% of the global population. In order to identify new …

Chronic visceral pain is the predominant symptom of functional gastrointestinal disorders
and chronic pancreatitis. Such pain can impair the patients' quality of life, and can also serve …

Intrinsic and extrinsic sensory neurons provide information about visceral distension, which
generally corresponds to the volume of luminal contents, the chemical composition and …

Chronic abdominal pain accompanying intestinal inflammation emerges from the
hyperresponsiveness of neuronal, immune and endocrine signaling pathways within the …

Chronic visceral pain is one of the most common reasons for patients with gastrointestinal
disorders, such as inflammatory bowel disease or disorders of brain-gut interaction, to seek …