The plastic nature of the vascular wall: a continuum of remodeling events contributing to control of arteriolar diameter and structure

LA Martinez-Lemus, MA Hill, GA Meininger - Physiology, 2009 - journals.physiology.org
The diameter of resistance arteries has a profound effect on the distribution of microvascular
blood flow and the control of systemic blood pressure. Here, we review mechanisms that …

Small artery remodeling: current concepts and questions

J Van Den Akker, MJC Schoorl, ENTP Bakker… - Journal of vascular …, 2010 - karger.com
Blood flow regulation by small arteries and arterioles includes adaptation of both vascular
tone and structure. It is becoming clear that tone and remodeling of resistance vessels are …

Mechanisms of the inward remodeling process in resistance vessels: is the actin cytoskeleton involved?

JA Castorena‐Gonzalez, MC Staiculescu… - …, 2014 - Wiley Online Library
The resistance arteries and arterioles are the vascular components of the circulatory system
where the greatest drop in blood pressure takes place. Consequently, these vessels play a …

Remodeling of blood vessels: responses of diameter and wall thickness to hemodynamic and metabolic stimuli

AR Pries, B Reglin, TW Secomb - Hypertension, 2005 - Am Heart Assoc
Vascular functions, including tissue perfusion and peripheral resistance, reflect continuous
structural adaptation (remodeling) of blood vessels in response to several stimuli. Here, a …

[HTML][HTML] Myogenic tone in peripheral resistance arteries and arterioles: the pressure is on!

WF Jackson - Frontiers in physiology, 2021 - frontiersin.org
Resistance arteries and downstream arterioles in the peripheral microcirculation contribute
substantially to peripheral vascular resistance, control of blood pressure, the distribution of …

Toward functional genomics of flow-induced outward remodeling of resistance arteries

JGR De Mey, PM Schiffers… - American Journal …, 2005 - journals.physiology.org
In resistance-sized arteries, a chronic increase in blood flow leads to increases in arterial
structural luminal diameter and arterial wall mass. In this review, we summarize recent …

Small artery remodeling in hypertension

MJ Mulvany - Current Hypertension Reports, 2002 - Springer
Hypertension is associated with altered structure of the resistance vessels, a process known
as remodeling. This review summarizes current concepts concerning the structure of a …

Adaptation of resistance arteries to increases in pressure

RL Prewitt, DC Rice, AD Dobrian - Microcirculation, 2002 - Taylor & Francis
During the development of hypertension, hypertrophy of smooth muscle cells and deposition
of extracellular matrix thicken the walls of large arteries without reducing the size of the …

Inward remodeling follows chronic vasoconstriction in isolated resistance arteries

ENTP Bakker, ET Van der Meulen… - Journal of vascular …, 2002 - karger.com
The hypothesis was tested that chronic vasoconstriction is followed by a structural reduction
in lumen diameter, measured at full dilation. An in vitro model of pressurized rat skeletal …

Structural autoregulation of terminal vascular beds: vascular adaptation and development of hypertension

AR Pries, TW Secomb, P Gaehtgens - Hypertension, 1999 - Am Heart Assoc
It is widely accepted that the early phase of primary hypertension is characterized by
elevated cardiac output, whereas in later stages the increased blood pressure is due to …