Bone Marrow Tumor Microenvironment of Obese Hodgkin Lymphoma Patients: implications of insulin axis
A Matos, J Marinho-Dias, S Ramalheira, S Roncon… - 2023 - researchsquare.com
Background Excessive adiposity, or obesity, has been associated with cancer promotion,
including an increased risk for developing Hodgkin Lymphoma (HL). However, the …
including an increased risk for developing Hodgkin Lymphoma (HL). However, the …
Mechanisms underlying the association between obesity and Hodgkin lymphoma
A Matos, J Marinho-Dias, S Ramalheira, MJ Oliveira… - Tumor Biology, 2016 - Springer
A solid body of knowledge indicates that overweight and obese subjects are prone to
develop cancer, aggressive disease, and death more than their lean counterparts. While …
develop cancer, aggressive disease, and death more than their lean counterparts. While …
The causal effect of adipose tissue on Hodgkin's lymphoma: two-sample Mendelian randomization study and validation
L Wu, F Liao, X Guo, N Li - Frontiers in Immunology, 2024 - frontiersin.org
Background Extensive research has been conducted on the correlation between adipose
tissue and the risk of malignant lymphoma. Despite numerous observational studies …
tissue and the risk of malignant lymphoma. Despite numerous observational studies …
Obesity and neoplasms of lymphohematopoietic cells
MA Lichtman - Blood Advances, 2016 - ashpublications.org
In countries such as the United States, where aggressive antismoking campaigns have led
to a striking decrease in the fraction of the population who are tobacco smokers, obesity is …
to a striking decrease in the fraction of the population who are tobacco smokers, obesity is …
The relation of obesity-related hormonal and cytokine levels with multiple myeloma and non-Hodgkin lymphoma
This article presents the first detailed overview of the mechanisms that may underlie the
relation of obesity with B-cell non-Hodgkin lymphomas (NHLs) and multiple myeloma (MM) …
relation of obesity with B-cell non-Hodgkin lymphomas (NHLs) and multiple myeloma (MM) …
Exploring the impact of body mass index on tumor biology and cancer development
J Ahrenfeldt, S Carstensen, IMH Eriksen… - Journal of Cancer …, 2024 - Springer
Purpose Cancer continues to be a major global health challenge, affecting millions of
individuals and placing substantial burdens on healthcare systems worldwide. Recent …
individuals and placing substantial burdens on healthcare systems worldwide. Recent …
[HTML][HTML] Bone marrow adipocyte shapes metabolism and immunity in tumor microenvironment to promote multiple myeloma
L Shu, J Li, S Chen, HY Huang, Y Li, Y Liang - Blood, 2021 - Elsevier
Multiple myeloma (MM) often occurs in middle-aged, elderly and obese patients with ectopic
accumulation of fat cells in the bone marrow. Bone marrow adipocytes (BMAs) display …
accumulation of fat cells in the bone marrow. Bone marrow adipocytes (BMAs) display …
Bone marrow microenvironment: roles and therapeutic implications in obesity-associated cancer
F Cheng, J He, J Yang - Trends in Cancer, 2023 - cell.com
Obesity is increasing globally and has been closely linked to the initiation and progression
of multiple human cancers. These relationships, to a large degree, are mediated through …
of multiple human cancers. These relationships, to a large degree, are mediated through …
Obesity is associated with an impaired survival in lymphoma patients undergoing autologous stem cell transplantation
Autologous hematopoietic stem cell transplantation (auto-HSCT) provides a potentially
curative treatment option for relapsed and refractory lymphomas. Obesity displays an …
curative treatment option for relapsed and refractory lymphomas. Obesity displays an …
[HTML][HTML] Obesity Is Associated with Increased Relapse Risk in Diffuse Large B-Cell Lymphoma
Abstract Introduction: Diffuse Large B-Cell Lymphoma (DLBCL) is an aggressive Non-
Hodgkin's lymphoma (NHL) characterized by clinical, biological and genetic heterogeneity …
Hodgkin's lymphoma (NHL) characterized by clinical, biological and genetic heterogeneity …