Genomic and environmental risk factors for cardiometabolic diseases in Africa: methods used for Phase 1 of the AWI-Gen population cross-sectional study

SA Ali, C Soo, G Agongo, M Alberts… - Global health …, 2018 - Taylor & Francis
There is an alarming tide of cardiovascular and metabolic disease (CMD) sweeping across
Africa. This may be a result of an increasingly urbanized lifestyle characterized by the …

H3Africa AWI-Gen Collaborative Centre: a resource to study the interplay between genomic and environmental risk factors for cardiometabolic diseases in four sub …

M Ramsay, N Crowther, E Tambo… - Global health …, 2016 - cambridge.org
Africa is experiencing a rapid increase in adult obesity and associated cardiometabolic
diseases (CMDs). The H3Africa AWI-Gen Collaborative Centre was established to examine …

Understanding the rise in cardiovascular diseases in Africa: harmonising H3Africa genomic epidemiological teams and tools: cardiovascular topic

MO Owolabi, D Adu, M Ramsay… - Cardiovascular journal of …, 2014 - journals.co.za
Cardiovascular diseases, principally ischaemic heart disease and stroke, are the leading
causes of global mortality and morbidity. Together with other non-communicable diseases …

Cohort Profile Update: Southall and Brent Revisited (SABRE) study: a UK population-based comparison of cardiovascular disease and diabetes in people of …

S Jones, T Tillin, C Park, S Williams… - International journal …, 2020 - academic.oup.com
Advance Access Publication Date: 13 October 2020 Cohort Profile from middle-to old-age.
This will further the aetiological understanding of heart failure, exercise intolerance and …

The genomic landscape of African populations in health and disease

CN Rotimi, AR Bentley, AP Doumatey… - Human molecular …, 2017 - academic.oup.com
A deeper appreciation of the complex architecture of African genomes is critical to the global
effort to understand human history, biology and differential distribution of disease by …

[HTML][HTML] Population genomics of cardiometabolic traits: design of the university college london-london school of hygiene and tropical medicine-edinburgh-bristol …

T Shah, J Engmann, C Dale, S Shah, J White… - PloS one, 2013 - journals.plos.org
Substantial advances have been made in identifying common genetic variants influencing
cardiometabolic traits and disease outcomes through genome wide association studies …

Cardiovascular disease risk factors and socio-economic position of Africans in transition: the THUSA study: cardiovascular topics

HH Vorster, A Kruger, CS Venter… - … journal of Africa, 2007 - journals.co.za
In many developing countries with advanced stages of the nutrition transition, the burden of
coronary artery disease (CAD) has shifted from the rich to the poor. in South Africa, it is …

Impact of socioeconomic status, ethnicity, and urbanization on risk factor profiles of cardiovascular disease in Africa

K Sliwa, L Acquah, BJ Gersh, AO Mocumbi - Circulation, 2016 - Am Heart Assoc
Africa is a continent characterized by marked ethnic, sociodemographic, and economic
diversity, with profound changes in many regions over the past 2 decades. This diversity has …

[HTML][HTML] An overview of cardiovascular risk factor burden in sub-Saharan African countries: a socio-cultural perspective

R BeLue, TA Okoror, J Iwelunmor, KD Taylor… - Globalization and …, 2009 - Springer
Abstract Background Sub-Saharan African (SSA) countries are currently experiencing one of
the most rapid epidemiological transitions characterized by increasing urbanization and …

[HTML][HTML] Obesity and cardio-metabolic risk factors in urban adults of Benin: relationship with socio-economic status, urbanisation, and lifestyle patterns

R Sodjinou, V Agueh, B Fayomi, H Delisle - BMC public health, 2008 - Springer
Background There is a dearth of information on diet-related chronic diseases in West Africa.
This cross-sectional study assessed the rate of obesity and other cardiovascular disease …