Taken together, herpesviruses that infect humans are responsible for multiple syndromes
involving many organ systems. Aside from a similar ultrastructural morphology and some …

Publisher Summary Herpesviruses have been identified that infect nearly all groups of
vertebrates. This chapter focuses on the latency of α-herpesviruses. Several mammalian …

Latency establishment is the hallmark feature of herpesviruses, a group of viruses, of which
nine are known to infect humans. They have co-evolved alongside their hosts, and mastered …

The epidemiology of herpes simplex virus (HSV) infections in man has a number of unusual
features (see Whitley, this volume). In particular, the recurrent lesions (herpes labialis …

During a long history of coevolution, herpesviruses have reached a fine-tuned balance with
their hosts, allowing them to successfully persist and spread to new hosts without causing …

The natural history of herpetic disease is a most intriguing phenomenon in virology, and its
definition has consumed the activities of a diverse group of individuals for the past three …

Eight members of the Herpesviridae family commonly infect humans, and close to 100% of
the adult population is infected with at least one of these. The five that cause the most health …

The sequence analysis of herpesviruses suggests they have been evolving with their
individual vertebrate hosts for millions of years, and their divergence parallels that of the …

Herpesviruses are among the most successful human pathogens. In healthy individuals,
primary infection is most often inapparent. After primary infection, the virus becomes latent in …

Ever since viruses were first discovered, towards the end of last century, there has been
much speculation as to their natures. Are they extrinsic agents, minute living micro …