Big data biology: Between eliminative inferences and exploratory experiments

E Ratti - Philosophy of Science, 2015 - cambridge.org
Recently, biologists have argued that data-driven biology fosters a new scientific
methodology, namely, one that is irreducible to traditional methodologies of molecular …

Plurality of explanatory strategies in biology: Mechanisms and networks

A Moreno, J Suárez - … prospects for scientific research: From pragmatism …, 2020 - Springer
Recent research in philosophy of science has shown that scientists rely on a plurality of
strategies to develop successful explanations of different types of phenomena. In the case of …

The challenges of big data biology

S Leonelli - Elife, 2019 - elifesciences.org
The availability of big data has the potential to transform many areas of the life sciences and
usher in new ways of doing research. Here, I argue that big data biology also raises …

Toward a notion of intervention in Big-data biology and molecular medicine

F Boem, E Ratti - Philosophy of Molecular Medicine, 2016 - taylorfrancis.com
We claim that in contemporary studies in molecular biology and biomedicine, the nature of
“manipulation” and “intervention” has changed. Traditionally, molecular biology and …

Perspective: Dimensions of the scientific method

EO Voit - PLOS Computational Biology, 2019 - journals.plos.org
The scientific method has been guiding biological research for a long time. It not only
prescribes the order and types of activities that give a scientific study validity and a stamp of …

From mechanisms to mathematical models and back to mechanisms: Quantitative mechanistic explanations

PA Braillard, C Malaterre, TM Baetu - … in biology: An enquiry into the …, 2015 - Springer
Despite the philosophical clash between deductive-nomological and mechanistic accounts
of explanation, in scientific practice, both approaches are required in order to achieve more …

Multilevel research strategies and biological systems

MA O'Malley, I Brigandt, AC Love, JW Crawford… - Philosophy of …, 2014 - cambridge.org
Multilevel research strategies characterize contemporary molecular inquiry into biological
systems. We outline conceptual, methodological, and explanatory dimensions of these …

[图书][B] Discovering complexity: Decomposition and localization as strategies in scientific research

W Bechtel, RC Richardson - 2010 - books.google.com
An analysis of two heuristic strategies for the development of mechanistic models, illustrated
with historical examples from the life sciences. In Discovering Complexity, William Bechtel …

The evolution of biology: A shift towards the engineering of prediction‐generating tools and away from traditional research practice

L Kelley, M Scott - EMBO reports, 2008 - embopress.org
Lawrence Kelley & Michael Scott one of the most interesting recent trends in the biosciences
has been the development of research methods that do not adhere to familiar standards of …

Shifting attention from theory to practice in philosophy of biology

CK Waters - New directions in the philosophy of science, 2014 - Springer
Traditional approaches in philosophy of biology focus attention on biological concepts,
explanations, and theories, on evidential support and inter-theoretical relations. Newer …