Blue light deprivation produces depression-like responses in Mongolian Gerbils

H Hu, C Kang, X Hou, Q Zhang, Q Meng, J Jiang… - Frontiers in …, 2020 - frontiersin.org
Background Depression is a leading cause of disability worldwide and is a major contributor
to the overall global burden of disease, but its etiology is poorly understood. It has been …

Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats

MMC Gonzalez, G Aston-Jones - Proceedings of the …, 2008 - National Acad Sciences
Light is an important environmental factor for regulation of mood. There is a high frequency
of seasonal affective disorder in high latitudes where light exposure is limited, and bright …

Melatonin modulates neuroinflammatory response and microglial activation in mice exposed to dim blue light at night

C Song, Z Suo, Z Wang, J Cao, Y Dong… - Frontiers in …, 2024 - frontiersin.org
Objectives Dim light at night contributes to neurodegenerative diseases by causing
neuroinflammation. In the central nervous system, the activation of microglia is a significant …

Neonatal exposure to constant light prevents anhedonia-like behavior induced by constant light exposure in adulthood

BJ Martynhak, D Correia, LH Morais, P Araujo… - Behavioural brain …, 2011 - Elsevier
Depressive episodes are associated with disturbances in circadian rhythms, and constant
illumination has been reported to induce depressive-like behavior in rodents. Rats kept in …

Light rescues circadian behavior and brain dopamine abnormalities in diurnal rodents exposed to a winter-like photoperiod

J Itzhacki, D Clesse, Y Goumon… - Brain Structure and …, 2018 - Springer
Seasonal affective disorder (SAD), beyond mood changes, is characterized by alterations in
daily rhythms of behavior and physiology. The pathophysiological conditions of SAD involve …

Blue light filtered white light induces depression-like responses and temporary spatial learning deficits in rats

Q Meng, Y Lian, J Jiang, W Wang, X Hou, Y Pan… - Photochemical & …, 2018 - Springer
Objectives: Ambient light has a vital impact on mood and cognitive functions. Blue light has
been previously reported to play a salient role in the antidepressant effect via melanopsin …

Decreased daytime illumination leads to anxiety-like behaviors and HPA axis dysregulation in the diurnal grass rat (Arvicanthis niloticus)

T Ikeno, SP Deats, J Soler, JS Lonstein, L Yan - Behavioural brain research, 2016 - Elsevier
The impact of ambient light on mood and anxiety is best exemplified in seasonal affective
disorder, in which patients experience depression and anxiety in winter when there is less …

Blue light insertion at night is involved in sleep and arousal-promoting response delays and depressive-like emotion in mice

F Wu, S Wu, Q Gui, K Tang, Q Xu, Y Tao… - Bioscience …, 2021 - portlandpress.com
Light plays a direct crucial role in the switch between sleep and arousal and the regulation
of physiology and behaviour, such as circadian rhythms and emotional change. Artificial …

Light Deprivation Induces Depression-Like Behavior and Suppresses Neurogenesis in Diurnal Mongolian Gerbil (Meriones unguiculatus)

BWM Lau, C Ren, J Yang, SWL Yan… - Cell …, 2011 - journals.sagepub.com
Recent evidence suggests that adult neurogenesis contributes to the pathophysiology of
different psychiatric disorders, including depressive disorder, anxiety disorder, and …

Effects of constant darkness on behaviour and physiology of male and female mice

D Singh, S Pandey, A Ghosh… - European Journal of …, 2023 - Wiley Online Library
A healthy state of life suggests not only a disease‐free condition but also normal
psychological functioning and behaviour. To maintain a healthy life, the duration of light …