Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules

MC Chen, FL Mi, ZX Liao, CW Hsiao, K Sonaje… - Advanced drug delivery …, 2013 - Elsevier
Chitosan (CS), a cationic polysaccharide, is widely regarded as a safe and efficient intestinal
absorption enhancer of therapeutic macromolecules, owing to its inherent mucoadhesive …

Advances and applications of chitosan-based nanomaterials as oral delivery carriers: A review

X Lang, T Wang, M Sun, X Chen, Y Liu - International journal of biological …, 2020 - Elsevier
The oral drug administration was convenient and comfortable route for patients.
Nevertheless, the oral uptake efficiency of many therapeutic agents was limited by …

[HTML][HTML] Potential applications of chitosan-based nanomaterials to surpass the gastrointestinal physiological obstacles and enhance the intestinal drug absorption

N Pathomthongtaweechai, C Muanprasat - Pharmaceutics, 2021 - mdpi.com
The small intestine provides the major site for the absorption of numerous orally
administered drugs. However, before reaching to the systemic circulation to exert beneficial …

[HTML][HTML] Recent advancement in chitosan-based nanoparticles for improved oral bioavailability and bioactivity of phytochemicals: Challenges and perspectives

SS Imam, S Alshehri, MM Ghoneim, A Zafar… - Polymers, 2021 - mdpi.com
The excellent therapeutic potential of a variety of phytochemicals in different diseases has
been proven by extensive studies throughout history. However, most phytochemicals are …

Targeted delivery of low molecular drugs using chitosan and its derivatives

JH Park, G Saravanakumar, K Kim, IC Kwon - Advanced drug delivery …, 2010 - Elsevier
Chitosan has prompted the continuous impetus for the development of safe and effective
drug delivery systems because of its unique physicochemical and biological characteristics …

[HTML][HTML] Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

Chitosan mediated targeted drug delivery system: a review

MP Patel, RR Patel, JK Patel - Journal of pharmacy & …, 2010 - journals.library.ualberta.ca
Chitosan has prompted the continuous movement for the development of safe and effective
drug delivery systems because of its unique physicochemical and biological characteristics …

Why Chitosan? From properties to perspective of mucosal drug delivery

A Kumar, A Vimal, A Kumar - International journal of biological …, 2016 - Elsevier
Non-parenteral drug delivery routes primarily remove the local pain at the injection site. The
drugs administered through the oral route encounter the process of hepatic first pass …

Chitosan and its derivatives as intestinal absorption enhancers

M Thanou, JC Verhoef, HE Junginger - Advanced drug delivery reviews, 2001 - Elsevier
Chitosan is a non-toxic, biocompatible polymer that has found a number of applications in
drug delivery including that of absorption enhancer of hydrophilic macromolecular drugs …

Oral drug absorption enhancement by chitosan and its derivatives

M Thanou, JC Verhoef, HE Junginger - Advanced drug delivery reviews, 2001 - Elsevier
Chitosan is a non-toxic, biocompatible polymer that has found a number of applications in
drug delivery including that of absorption enhancer of hydrophilic macromolecular drugs …