Hepatic radiofrequency ablation–induced stimulation of distant tumor growth is suppressed by c-Met inhibition

M Ahmed, G Kumar, M Moussa, Y Wang, N Rozenblum… - Radiology, 2016 - pubs.rsna.org
Purpose To elucidate how hepatic radiofrequency (RF) ablation affects distant extrahepatic
tumor growth by means of two key molecular pathways. Materials and Methods Rats were …

Radiofrequency ablation: inflammatory changes in the periablative zone can induce global organ effects, including liver regeneration

N Rozenblum, E Zeira, B Bulvik, S Gourevitch, H Yotvat… - Radiology, 2015 - pubs.rsna.org
Purpose To determine the kinetics of innate immune and hepatic response to the
coagulation necrosis area that remains in situ after radiofrequency (RF) ablation, the …

Hepatic thermal ablation: effect of device and heating parameters on local tissue reactions and distant tumor growth

E Velez, SN Goldberg, G Kumar, Y Wang, S Gourevitch… - Radiology, 2016 - pubs.rsna.org
Purpose To determine whether variable hepatic microwave ablation (MWA) can induce local
inflammation and distant pro-oncogenic effects compared with hepatic radiofrequency …

Hepatic radiofrequency ablation: markedly reduced systemic effects by modulating periablational inflammation via cyclooxygenase-2 inhibition

G Kumar, SN Goldberg, Y Wang, E Velez… - European …, 2017 - Springer
Objectives To determine whether celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, can
potentiate hepatic radiofrequency ablation (RFA)-induced local cellular infiltration and …

Oncogenesis: an “off-target” effect of radiofrequency ablation

N Rozenblum, E Zeira, V Scaiewicz, B Bulvik… - Radiology, 2015 - pubs.rsna.org
Purpose To compare hepatocellular carcinoma (HCC) development after radiofrequency
(RF) ablation, partial surgical hepatectomy, and a sham operation and to inhibit HCC …

[HTML][HTML] Insufficient radiofrequency ablation treated hepatocellular carcinoma cells promote metastasis by up-regulation ITGB3

N Zhang, D Ma, L Wang, X Zhu, Q Pan, Y Zhao… - Journal of …, 2017 - ncbi.nlm.nih.gov
Radiofrequency ablation (RFA) is one of the standards of care for early stage hepatocellular
carcinoma (HCC). However, rapid progression of residual tumor after RFA has been …

Insufficient radiofrequency ablation promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells through Akt and ERK signaling pathways

S Dong, J Kong, F Kong, J Kong, J Gao, S Ke… - Journal of Translational …, 2013 - Springer
Background Residual tumor progression after insufficient radiofrequency ablation (RFA) has
been recently reported. However, whether epithelial-mesenchymal transition (EMT), which is …

Low temperature of radiofrequency ablation at the target sites can facilitate rapid progression of residual hepatic VX2 carcinoma

S Ke, X Ding, J Kong, J Gao, S Wang, Y Cheng… - Journal of translational …, 2010 - Springer
Background Rapid progression of residual tumor after radiofrequency ablation (RFA) of
hepatocellular carcinoma has been observed increasingly. However, its underlying …

Sorafenib suppresses the rapid progress of hepatocellular carcinoma after insufficient radiofrequency ablation therapy: An experiment in vivo

M Xu, X Xie, X Xie, Z Xu, G Liu, Y Zheng… - Acta …, 2013 - journals.sagepub.com
Background Radiofrequency ablation (RFA) is a widely applied treatment for hepatocellular
carcinoma (HCC), but insufficient RFA can promote rapid progression of the residual tumor …

[PDF][PDF] Sublethal heat treatment promotes epithelial‐mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma

S Yoshida, M Kornek, N Ikenaga, M Schmelzle… - …, 2013 - Wiley Online Library
Radiofrequency ablation (RFA) is a potentially curative therapy for hepatocellular carcinoma
(HCC). However, incomplete RFA can induce accelerated invasive growth at the periphery …