Serum amyloid A, the major vertebrate acute‐phase reactant

CM Uhlar, AS Whitehead - European journal of biochemistry, 1999 - Wiley Online Library
The serum amyloid A (SAA) family comprises a number of differentially expressed
apolipoproteins, acute‐phase SAAs (A‐SAAs) and constitutive SAAs (C‐SAAs). A‐SAAs are …

Regulation of serum amyloid A protein expression during the acute-phase response

LE Jensen, AS WHITEHEAD - Biochemical Journal, 1998 - portlandpress.com
The acute-phase (AP) serum amyloid A proteins (A-SAA) are multifunctional apolipoproteins
which are involved in cholesterol transport and metabolism, and in modulating numerous …

Acute-phase serum amyloid A: perspectives on its physiological and pathological roles

R Kisilevsky, PN Manley - Amyloid, 2012 - Taylor & Francis
Serum amyloid A (SAA), a protein originally of interest primarily to investigators focusing on
AA amyloidogenesis, has become a subject of interest to a very broad research community …

Role of serum amyloid A during metabolism of acute-phase HDL by macrophages

A Artl, G Marsche, S Lestavel, W Sattler… - … , and vascular biology, 2000 - Am Heart Assoc
The serum amyloid A (SAA) family of proteins is encoded by multiple genes that display
allelic variation and a high degree of homology in mammals. Triggered by inflammation after …

Emerging functions of serum amyloid A in inflammation

RD Ye, L Sun - Journal of Leucocyte Biology, 2015 - academic.oup.com
SAA is a major acute-phase protein produced in large quantity during APR. The rise of SAA
concentration in blood circulation during APR has been a clinical marker for active …

Serum amyloid A (SAA): an acute phase protein and apolipoprotein

E Malle, A Steinmetz, JG Raynes - Atherosclerosis, 1993 - Elsevier
Serum amyloid A (SAA) proteins comprise a family of apolipoproteins coded for by at least
three genes with allelic variation and a high degree of homology between species. The …

[HTML][HTML] Serum amyloid A and protein AA: molecular mechanisms of a transmissible amyloidosis

GT Westermark, P Westermark - FEBS letters, 2009 - Elsevier
Systemic AA-amyloidosis is a complication of chronic inflammatory diseases and the fibril
protein AA derives from the acute phase reactant serum AA. AA-amyloidosis can be induced …

Extrahepatic production of acute phase serum amyloid A.

N Upragarin, WJ Landman, W Gaastra… - Histology and …, 2005 - europepmc.org
Amyloidosis is a group of diseases characterized by the extracellular deposition of protein
that contains non-branching, straight fibrils on electron microscopy (amyloid fibrils) that have …

Structure and expression of different serum amyloid A (SAA) variants and their concentration-dependent functions during host insults

M De Buck, M Gouwy, J Ming Wang… - Current medicinal …, 2016 - ingentaconnect.com
Serum amyloid A (SAA) is, like C-reactive protein (CRP), an acute phase protein and can be
used as a diagnostic, prognostic or therapy follow-up marker for many diseases. Increases …

Serum amyloid A (SAA) proteins

GH Sack - … Respiratory Proteins, Lipoproteins and Other Body …, 2020 - Springer
As normal constituents of blood serum, the Serum Amyloid A (SAA) proteins are small (104
amino acids in humans) and remarkably well-conserved in mammalian evolution. They are …