Introduction Currently available treatments for osteoarthritis (OA) are restricted to
nonsteroidal anti-inflammatory drugs, which exhibit numerous side effects and are only …

Introduction Osteoarthritis (OA) and rheumatoid arthritis (RA) are characterised by joint
inflammation and cartilage degradation. Although mesenchymal stem cell (MSC)-like …

Pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-
α) play a key role in the pathogenesis of osteoarthritis (OA). Anti-inflammatory agents …

Osteoarthritis is a degenerative disease of the joint affecting aging populations worldwide. It
has an underlying inflammatory cause, which contributes to the loss of chondrocytes …

Background Curcumin has been shown to have chondroprotective potential in vitro.
However, its effect on disease and symptom modification in osteoarthritis (OA) is largely …

Curcumin has shown protective potential on osteoarthritis. However, its effect on treatment of
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …

Resveratrol is a natural polyphenolic compound that prevents inflammation in chondrocytes
and animal models of osteoarthritis (OA) via yet to be defined mechanisms. The purpose of …

OBJECTIVES: Curcumin (diferuloylmethane) is the principal biochemical component of the
spice turmeric and has been shown to possess potent anti-catabolic, anti-inflammatory and …

Osteoarthritis is an inflammatory disease of load-bearing synovial joints that is currently
treated with drugs that exhibit numerous side effects and are only temporarily effective on …

Objective and design This study aims to investigate the effects of curcumin (Cur) on the
extracellular matrix protein metabolism of articular chondrocytes and on their production of …