The NF-κB family of dimeric transcription factors regulate diverse biological functions. Their
cellular expression profiles differ, which lead to different concentrations in different …

The transcription regulators of the NF-κB family have emerged as a critical factor affecting
the function of various adult tissues. The NF-κB family transcription factors are homo-and …

B cell leukemia 3 (Bcl-3) is an essential negative regulator of NF-κB during Toll-like receptor
and TNF receptor signaling. Bcl-3 also interacts with a number of transcriptional regulators …

IκB proteins control the subcellular localization and DNA binding activity of NF-κB
transcription factors. BCL3 is a nuclear IκB that can inhibit or enhance the binding of NF-κB …

BCL-6 is a transcription repressor frequently deregulated in non-Hodgkin's B cell
lymphomas. Its activity is also critical to germinal center development and balanced Th1/Th2 …

Unlike prototypical IκB proteins, which are inhibitors of NF-κB RelA, cRel, and RelB dimers,
the atypical IκB protein Bcl3 is primarily a transcriptional coregulator of p52 and p50 …

Transcription factors of the NF-κB/Rel family are retained in the cytoplasm as inactive
complexes through association with IκB inhibitory proteins. Several NF-κB activators induce …

The transcription factor, NF-κB (nuclear factor-κB) and associated regulatory factors make up
a multi-component signaling pathway that regulates a wide range of biological processes …

Abstract The NF-κB/Rel signalling pathway plays a crucial role in numerous biological
processes, including innate and adaptive immunity. NF-κB is a family of transcription factors …

The activity of the rel/NF-κB/dorsal family of κB site binding proteins is regulated by IκB
proteins. The ankyrin repeat motif identified in IκB family members, which include IκBα …