Chinmedomics: a potent tool for the evaluation of traditional Chinese medicine efficacy and identification of its active components

M Wang, F Yin, L Kong, L Yang, H Sun, Y Sun, G Yan… - Chinese Medicine, 2024 - Springer
As an important part of medical science, Traditional Chinese Medicine (TCM) attracts much
public attention due to its multi-target and multi-pathway characteristics in treating diseases …

[HTML][HTML] Chinmedomics: a powerful approach integrating metabolomics with serum pharmacochemistry to evaluate the efficacy of traditional Chinese medicine

AH Zhang, H Sun, GL Yan, Y Han, QQ Zhao, XJ Wang - Engineering, 2019 - Elsevier
Abstract Evaluation of the efficacy of traditional Chinese medicines (TCMs) is an important
prerequisite for discovering effective substances, lead compounds, and quality markers (Q …

Multi-omics approaches for in-depth understanding of therapeutic mechanism for Traditional Chinese Medicine

X Zhu, Q Yao, P Yang, D Zhao, R Yang… - Frontiers in …, 2022 - frontiersin.org
Traditional Chinese Medicine (TCM) is extensively utilized in clinical practice due to its
therapeutic and preventative treatments for various diseases. With the development of high …

Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines

Y Han, H Sun, A Zhang, G Yan, X Wang - Pharmacology & Therapeutics, 2020 - Elsevier
Herbal medicines have accumulated valuable clinical experience in thousands of years of
applications in traditional Chinese medicine (TCM) or ethnomedicine. The unique multi …

Metabolomics deciphering therapeutic effects and mechanism of traditional chinese medicines

WW Ma, AH Zhang, H Sun, XC Meng… - World Journal of …, 2016 - journals.lww.com
Traditional Chinese medicine (TCM), an ancient medical system, has the advantages of
multi-targeting and multi-ingredient preparations, and is different from modern …

Deciphering the toxicity-effect relationship and action patterns of traditional Chinese medicines from a smart data perspective: a comprehensive review

Y Li, X Deng, H Xiong, Q Hu, Y Chen… - Frontiers in …, 2023 - frontiersin.org
In Chinese medicine, the primary considerations revolve around toxicity and effect. The
clinical goal is to achieve maximize effect while minimizing toxicity. Nevertheless, both …

Future perspectives of Chinese medical formulae: chinmedomics as an effector

X Wang, A Zhang, H Sun - Omics: a journal of integrative biology, 2012 - liebertpub.com
Traditional Chinese medicine (TCM) has been used for thousands of years to treat or
prevent disease. The health care paradigm has shifted from a focus on disease to TCM …

BATMAN-TCM: a bioinformatics analysis tool for molecular mechANism of traditional Chinese medicine

Z Liu, F Guo, Y Wang, C Li, X Zhang, H Li, L Diao… - Scientific reports, 2016 - nature.com
Abstract Traditional Chinese Medicine (TCM), with a history of thousands of years of clinical
practice, is gaining more and more attention and application worldwide. And TCM-based …

Potential role of metabolomic approaches for Chinese medicine syndromes and herbal medicine

H Sun, A Zhang, X Wang - Phytotherapy Research, 2012 - Wiley Online Library
Systems biology has significantly increased in recent years. Its method and design resemble
those of traditional Chinese medicine (TCM), which is a unique medical system that assisted …

Multi-level advances in databases related to systems pharmacology in traditional Chinese medicine: a 60-year review

M Fan, C Jin, D Li, Y Deng, L Yao, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The therapeutic effects of traditional Chinese medicine (TCM) involve intricate interactions
among multiple components and targets. Currently, computational approaches play a pivotal …