Optogenetics
MGP Segala, LL Looger - Molecular imaging, 2021 - Elsevier
We review the state of the art in optogenetics—the use of light to control processes in cells,
tissues, and intact (often behaving) organisms. We focus on the available genetically …
tissues, and intact (often behaving) organisms. We focus on the available genetically …
[HTML][HTML] The optogenetic (r) evolution
ML Rein, JM Deussing - Molecular Genetics and Genomics, 2012 - Springer
Optogenetics is a rapidly evolving field of technology that allows optical control of genetically
targeted biological systems at high temporal and spatial resolution. By heterologous …
targeted biological systems at high temporal and spatial resolution. By heterologous …
Optogenetics: Rho GTPases activated by light in living macrophages
M Hülsemann, PV Verkhusha, P Guo, V Miskolci… - Immune Mediators in …, 2020 - Springer
Genetically encoded optogenetic tools are increasingly popular and useful for perturbing
signaling pathways with high spatial and temporal resolution in living cells. Here, we show …
signaling pathways with high spatial and temporal resolution in living cells. Here, we show …
Optogenetic tools for mammalian systems
K Müller, W Weber - Molecular BioSystems, 2013 - pubs.rsc.org
Light is fundamental to life on earth. Therefore, nature has evolved a multitude of
photoreceptors that sense light across all kingdoms. This natural resource provides synthetic …
photoreceptors that sense light across all kingdoms. This natural resource provides synthetic …
Optogenetics for light control of biological systems
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
[图书][B] Opsin-free Optogenetics: Technology and Applications
Optogenetics represents a breakthrough technology capable of dynamically modulating
molecular and cellular activity in live cells with high precision. This transformative …
molecular and cellular activity in live cells with high precision. This transformative …
Optophysiology: Illuminating cell physiology with optogenetics
Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …
and organisms with tailored functions. Optogenetics has the advantages of …
The promise of optogenetics in cell biology: interrogating molecular circuits in space and time
Optogenetic modules offer cell biologists unprecedented new ways to poke and prod cells.
The combination of these precision perturbative tools with observational tools, such as …
The combination of these precision perturbative tools with observational tools, such as …
[引用][C] The rise of molecular optogenetics
B Di Ventura, W Weber - Advanced Biology, 2021 - Wiley Online Library
DOI: 10.1002/adbi. 202100776 messenger-producing enzymes, light-inducible
transcriptional regulators, or tools to steer the translocation of proteins between different …
transcriptional regulators, or tools to steer the translocation of proteins between different …