Optogenetics

MGP Segala, LL Looger - Molecular imaging, 2021 - Elsevier
We review the state of the art in optogenetics—the use of light to control processes in cells,
tissues, and intact (often behaving) organisms. We focus on the available genetically …

[HTML][HTML] The optogenetic (r) evolution

ML Rein, JM Deussing - Molecular Genetics and Genomics, 2012 - Springer
Optogenetics is a rapidly evolving field of technology that allows optical control of genetically
targeted biological systems at high temporal and spatial resolution. By heterologous …

Optogenetics: Rho GTPases activated by light in living macrophages

M Hülsemann, PV Verkhusha, P Guo, V Miskolci… - Immune Mediators in …, 2020 - Springer
Genetically encoded optogenetic tools are increasingly popular and useful for perturbing
signaling pathways with high spatial and temporal resolution in living cells. Here, we show …

Optogenetic tools for mammalian systems

K Müller, W Weber - Molecular BioSystems, 2013 - pubs.rsc.org
Light is fundamental to life on earth. Therefore, nature has evolved a multitude of
photoreceptors that sense light across all kingdoms. This natural resource provides synthetic …

Optogenetics for light control of biological systems

V Emiliani, E Entcheva, R Hedrich… - Nature Reviews …, 2022 - nature.com
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

[图书][B] Opsin-free Optogenetics: Technology and Applications

Y Zhou, K Zhang - 2022 - books.google.com
Optogenetics represents a breakthrough technology capable of dynamically modulating
molecular and cellular activity in live cells with high precision. This transformative …

Optophysiology: Illuminating cell physiology with optogenetics

P Tan, L He, Y Huang, Y Zhou - Physiological reviews, 2022 - journals.physiology.org
Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …

[图书][B] Optogenetics and Electrophysiology

H Tseng, RE Kohman, X Han - 2015 - books.google.com
Optogenetics combines optical and genetic techniques to manipulate neural activity. Genetic
techniques are used to transduce neurons of interest in the brain with light-sensitive …

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

JE Toettcher, CA Voigt, OD Weiner, WA Lim - Nature methods, 2011 - nature.com
Optogenetic modules offer cell biologists unprecedented new ways to poke and prod cells.
The combination of these precision perturbative tools with observational tools, such as …

[引用][C] The rise of molecular optogenetics

B Di Ventura, W Weber - Advanced Biology, 2021 - Wiley Online Library
DOI: 10.1002/adbi. 202100776 messenger-producing enzymes, light-inducible
transcriptional regulators, or tools to steer the translocation of proteins between different …