Residential radon, EGFR mutations and ALK alterations in never-smoking lung cancer cases

A Ruano-Ravina, M Torres-Durán… - European …, 2016 - Eur Respiratory Soc
The aim of this study was to assess if residential radon exposure might cause EGFR
mutations or ALK rearrangements in never-smokers. We designed a multicentre case …

Indoor radon in EGFR-and BRAF-mutated and ALK-rearranged non–small-cell lung cancer patients

L Mezquita, A Benito, A Ruano-Ravina, J Zamora… - Clinical Lung Cancer, 2019 - Elsevier
Background Radon gas is the leading cause of lung cancer in the nonsmoking population.
The World Health Organization (WHO) recommends indoor concentrations of< 100 Bq/m³ …

[HTML][HTML] Gene mutation discovery research of non-smoking lung cancer patients due to indoor radon exposure

JR Choi, SY Park, OK Noh, YW Koh… - Annals of occupational and …, 2016 - Springer
Although the incidence and mortality for most cancers such as lung and colon are
decreasing in several countries, they are increasing in several developed countries because …

[HTML][HTML] Radon and lung cancer: current trends and future perspectives

M Riudavets, M Garcia de Herreros, B Besse… - Cancers, 2022 - mdpi.com
Simple Summary Radon represents the main risk factor of lung cancer in non-smokers and
the second one in smoking patients. In Europe, there are several radon-prone areas, but …

Indoor radon exposure increases tumor mutation burden in never-smoker patients with lung adenocarcinoma

SM Lim, JW Choi, MH Hong, D Jung, CY Lee, SY Park… - Lung Cancer, 2019 - Elsevier
Objectives Radon, a natural radiation, is the leading environmental cause of lung cancer in
never-smokers. However, the radon exposure impact on the mutational landscape and …

Lung cancer in never-smokers: radon exposure and environmental tobacco smoke

BBM Melloni - European Respiratory Journal, 2014 - Eur Respiratory Soc
Lung cancer occurs in subjects with no history of active smoking in 15–25% of all cases,
mainly females. Lung cancer in never-smokers is a recent field of investigation, with …

Lung cancer survival in never-smokers and exposure to residential radon: results of the LCRINS study

A Casal-Mourino, A Ruano-Ravina, M Torres-Duran… - Cancer Letters, 2020 - Elsevier
We aimed to evaluate lung cancer survival in never-smokers, both overall and specifically by
sex, exposure to residential-radon, age, histological type, and diagnostic stage. We included …

Residential radon and lung cancer characteristics in never smokers

M Torres-Duran, A Ruano-Ravina… - … journal of radiation …, 2015 - Taylor & Francis
Purpose: The aim of this study is to assess if there is a relationship between residential
radon and lung cancer histological types and patients' age at diagnosis. Materials and …

Lung cancer and residential radon in never-smokers: A pooling study in the Northwest of Spain

M Lorenzo-González, A Ruano-Ravina… - Environmental …, 2019 - Elsevier
Background Using a pooled case-control study design, including only never-smokers, we
have assessed the association of residential radon exposure with the subsequent …

p53 Mutations in Lung Cancer Associated with Residential Radon Exposure

A Yngveson, C Williams, A Hjerpe, J Lundeberg… - … Biomarkers & Prevention, 1999 - AACR
Unusual mutation patterns in lung tumors among underground miners have been indicated,
suggesting radon-specific alterations in the genome, but the data are not consistent. To …